{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:03:10Z","timestamp":1740164590505,"version":"3.37.3"},"reference-count":11,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Hematology"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>Herein, the first case of childhood erythrophagocytosis following chemotherapy for erythroleukemia in a child with monosomy 7 is reported. A 5-year-old boy presented with anemia, thrombocytopenia, and hepatosplenomegaly in whom erythroleukemia was diagnosed. Prolonged pancytopenia accompanied by persistent fever and huge splenomegaly and hepatomegaly became evident after 2 courses of chemotherapy. On bone marrow aspiration, macrophages phagocytosing erythroid precursors were observed and the diagnosis of HLH was established; additionally, monosomy 7 was detected on bone marrow cytogenetic examination. In conclusion, monosomy 7 can lead to erythrophagocytosis associated with erythroid leukemia and should be considered among the chromosomal abnormalities contributing to the association.<\/jats:p>","DOI":"10.1155\/2013\/581073","type":"journal-article","created":{"date-parts":[[2013,12,12]],"date-time":"2013-12-12T16:03:24Z","timestamp":1386864204000},"page":"1-3","source":"Crossref","is-referenced-by-count":0,"title":["Hemophagocytic Lymphohistiocytosis Complicating Erythroleukemia in a Child with Monosomy 7: A Case Report and Review of the Literature"],"prefix":"10.1155","volume":"2013","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3258-5627","authenticated-orcid":true,"given":"Samin","family":"Alavi","sequence":"first","affiliation":[{"name":"Pediatric Congenital Hematologic Disorders Research Center, Shahid Beheshti University of Medical Sciences, Mofid Children\u2019s Hospital, Tehran 15468-15514, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Ebadi","sequence":"additional","affiliation":[{"name":"Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alireza","family":"Jenabzadeh","sequence":"additional","affiliation":[{"name":"Pediatric Congenital Hematologic Disorders Research Center, Shahid Beheshti University of Medical Sciences, Mofid Children\u2019s Hospital, Tehran 15468-15514, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. T.","family":"Arzanian","sequence":"additional","affiliation":[{"name":"Pediatric Congenital Hematologic Disorders Research Center, Shahid Beheshti University of Medical Sciences, Mofid Children\u2019s Hospital, Tehran 15468-15514, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6897-5451","authenticated-orcid":true,"given":"Sh.","family":"Shamsian","sequence":"additional","affiliation":[{"name":"Pediatric Congenital Hematologic Disorders Research Center, Shahid Beheshti University of Medical Sciences, Mofid Children\u2019s Hospital, Tehran 15468-15514, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2010.08544.x"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.11704"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2009.08.027"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-4608(00)00268-5"},{"issue":"3","key":"5","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1002\/1097-0142(19910801)68:3<540::AID-CNCR2820680316>3.0.CO;2-F","volume":"68","year":"1991","journal-title":"Cancer"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1186\/1752-1947-2-319"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/s12185-010-0661-2"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcl.2012.03.002"},{"issue":"4","key":"9","first-page":"383","volume":"13","year":"1991","journal-title":"Clinical & Laboratory Haematology"},{"issue":"8","key":"10","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1097\/01.mph.0000212964.75630.5d","volume":"28","year":"2006","journal-title":"Journal of Pediatric Hematology\/Oncology"},{"issue":"18","key":"11","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.2169\/internalmedicine.48.1798","volume":"48","year":"2009","journal-title":"Internal Medicine"}],"container-title":["Case Reports in Hematology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2013\/581073.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2013\/581073.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2013\/581073.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,22]],"date-time":"2017-06-22T00:09:56Z","timestamp":1498090196000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crihem\/2013\/581073\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":11,"alternative-id":["581073","581073"],"URL":"https:\/\/doi.org\/10.1155\/2013\/581073","relation":{},"ISSN":["2090-6560","2090-6579"],"issn-type":[{"type":"print","value":"2090-6560"},{"type":"electronic","value":"2090-6579"}],"subject":[],"published":{"date-parts":[[2013]]}}}