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Chromatographic separation was carried out on an Acquity BEH C<jats:sub>18<\/jats:sub>column (100\u2009mm \u00d7 2.1\u2009mm, 1.7\u2009<jats:italic>\u03bc<\/jats:italic>m) with gradient elution of acetonitrile and 0.10% formic acid (v\/v) at a flow rate of 0.4\u2009mL\/min, and column temperature 30\u00b0C. The developed method was validated in terms of linearity, accuracy, precision, stability, and sensitivity. The optimized method was successfully applied to analyze twenty-two<jats:italic>G. biloba<\/jats:italic>leaf samples of fruit cultivars collected from different places in China. Furthermore, hierarchical clustering analysis (HCA) was performed to evaluate and classify the samples according to the contents of the twenty-four chemical constituents. All of the results demonstrated that the developed method was useful for the overall evaluation of the quality of<jats:italic>G. biloba<\/jats:italic>leaves, and this study was also helpful for the comprehensive utilization and development of<jats:italic>G. biloba<\/jats:italic>resources.<\/jats:p>","DOI":"10.1155\/2013\/582591","type":"journal-article","created":{"date-parts":[[2012,12,27]],"date-time":"2012-12-27T21:02:22Z","timestamp":1356642142000},"page":"1-11","source":"Crossref","is-referenced-by-count":16,"title":["Simultaneous Quantification of Flavonol Glycosides, Terpene Lactones, Biflavones, Proanthocyanidins, and Ginkgolic Acids in<i>Ginkgo biloba<\/i>Leaves from Fruit Cultivars by Ultrahigh-Performance Liquid Chromatography Coupled with Triple Quadrupole Mass Spectrometry"],"prefix":"10.1155","volume":"2013","author":[{"given":"Xin","family":"Yao","sequence":"first","affiliation":[{"name":"Jiangsu Key Laboratory for High Technology of TCM Formulae Research, Nanjing 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