{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:43:44Z","timestamp":1761561824533},"reference-count":24,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"National Science and Technology Major Projects"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. To explore the efficacy of Herb-partitioned moxibustion in treating IBS-D patients.<jats:italic>Method<\/jats:italic>. 210 IBS-D patients were randomly assigned on a<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mn>3<\/mml:mn><mml:mo>:<\/mml:mo><mml:mn>3<\/mml:mn><mml:mo>:<\/mml:mo><mml:mn>2<\/mml:mn><\/mml:math>basis to group HM, group FM, or group PB for 4-week treatment. The change of GSRS total score at weeks 4 and 8, the changes of GSRS specific scores, and adverse events were evaluated.<jats:italic>Results<\/jats:italic>. Patients in group HM and group FM had lower GSRS total score at week 4 (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mn>1.98<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>0.303<\/mml:mn><\/mml:math>,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mn>2.93<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>0.302<\/mml:mn><\/mml:math>versus<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mn>3.73<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>0.449<\/mml:mn><\/mml:math>) and at week 8 (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mn>2.75<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>0.306<\/mml:mn><\/mml:math>,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mn>3.56<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>0.329<\/mml:mn><\/mml:math>versus<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mn>4.39<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>2.48<\/mml:mn><\/mml:math>) as compared with patients\u2019 score in group PB. However, there was no significant difference of GSRS total score between group HM and group FM. The effect of HM was significantly greater than that of orally taking PB in ameliorating the symptoms of rugitus (0.38 versus 0.59,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:math>), abdominal pain (0.28 versus 0.57,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M9\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.01<\/mml:mn><\/mml:math>), abdominal distension (0.4 versus 0.7,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M10\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.01<\/mml:mn><\/mml:math>), and increased passage of stools (0.06 versus 0.25,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M11\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.01<\/mml:mn><\/mml:math>) at the end of treatment period. In the follow-up period, patients\u2019 therapeutic effect in group HM remained greater than that in group FM (in abdominal pain, abdominal distension, and increased passage of stools) and that in group PB (in loose stools).<jats:italic>Conclusions<\/jats:italic>. HM appears to be a promising, efficacious, and well-tolerated treatment for patients with IBS-D.<\/jats:p>","DOI":"10.1155\/2013\/605460","type":"journal-article","created":{"date-parts":[[2013,12,19]],"date-time":"2013-12-19T21:03:32Z","timestamp":1387487012000},"page":"1-8","source":"Crossref","is-referenced-by-count":12,"title":["Randomized Clinical Trial: The Clinical Effects of Herb-Partitioned Moxibustion in Patients with Diarrhoea-Predominant Irritable Bowel Syndrome"],"prefix":"10.1155","volume":"2013","author":[{"given":"Yu-xia","family":"Ma","sequence":"first","affiliation":[{"name":"Shandong University of Traditional Chinese Medicine, Shandong, Jinan 250014, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Liu","sequence":"additional","affiliation":[{"name":"Shandong University of Traditional Chinese Medicine, Shandong, Jinan 250014, 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