{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T23:07:16Z","timestamp":1724972836128},"reference-count":25,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pregnancy"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. We conducted the study to see the incidence of thyroid dysfunction in women with obstetrical high-risk factors.<jats:italic>Methods<\/jats:italic>. We retrospectively reviewed medical charts of high-risk pregnant women who had examination for thyroid function during pregnancy. Women were divided according to clinical presentation, symptoms of thyroid disease and those with a personal history of thyroid disease (thyroid disease,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>32<\/mml:mn><\/mml:math>), intrauterine growth restriction (IUGR,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>115<\/mml:mn><\/mml:math>), diabetes mellitus (diabetes,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>115<\/mml:mn><\/mml:math>), hypertension (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>63<\/mml:mn><\/mml:math>), intrauterine fetal death (IUFD,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>52<\/mml:mn><\/mml:math>), and placental abruption (abruption,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>15<\/mml:mn><\/mml:math>). The incidence of thyroid dysfunctions including hyperthyroidism or hypothyroidism was compared.<jats:italic>Results<\/jats:italic>. The overall prevalence of thyroid dysfunction was 24.7%. The incidence of thyroid dysfunction in each group was as follows: 31% in thyroid disease, 25% in IUGR, 30% in diabetes, 27% in hypertension, 12% in IUFD, and 7% in abruption. Except IUFD, the incidence was not statistically significant from the group of thyroid disease (thyroid disease versus IUFD,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.03<\/mml:mn><\/mml:math>by<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\"><mml:mrow><mml:msup><mml:mrow><mml:mi>\u03c7<\/mml:mi><\/mml:mrow><mml:mrow><mml:mn>2<\/mml:mn><\/mml:mrow><\/mml:msup><\/mml:mrow><\/mml:math>test). Thyroid disease represented for only 10% of all thyroid dysfunctions.<jats:italic>Conclusion<\/jats:italic>. Testing of women with a personal history or current symptoms of thyroid disease during pregnancy may be insufficient to detect women with thyroid dysfunction, who will become at high-risk pregnancy.<\/jats:p>","DOI":"10.1155\/2013\/619718","type":"journal-article","created":{"date-parts":[[2013,3,27]],"date-time":"2013-03-27T17:01:56Z","timestamp":1364403716000},"page":"1-5","source":"Crossref","is-referenced-by-count":12,"title":["Risk-Based Screening for Thyroid Dysfunction during Pregnancy"],"prefix":"10.1155","volume":"2013","author":[{"given":"Masanao","family":"Ohashi","sequence":"first","affiliation":[{"name":"Department of Obstetrics & Gynecology, Miyazaki Medical Association Hospital, 738-1 Shinbepputyo-Funato, Miyazaki 880-0834, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seishi","family":"Furukawa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynecology, Faculty of Medicine, University of Miyazaki, 5200 Kihara-Kiyotake, Miyazaki 889-1692, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaori","family":"Michikata","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynecology, Miyazaki Medical Association Hospital, 738-1 Shinbepputyo-Funato, Miyazaki 880-0834, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuhide","family":"Kai","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynecology, Miyazaki Medical Association Hospital, 738-1 Shinbepputyo-Funato, Miyazaki 880-0834, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Sameshima","sequence":"additional","affiliation":[{"name":"Department of Obstetrics & Gynecology, Faculty of Medicine, University of Miyazaki, 5200 Kihara-Kiyotake, Miyazaki 889-1692, 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