{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:14:31Z","timestamp":1761513271750,"version":"3.37.3"},"reference-count":19,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Neurological Medicine"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. Several tests are available in the diagnostics of sporadic Creutzfeldt-Jakob disease (sCJD); however, none of these is conclusive. We review the values of these tests, from an intensive care unit (ICU) perspective.<jats:italic>Methods<\/jats:italic>. Case report and review of the literature.<jats:italic>Results<\/jats:italic>. A 53-year-old woman initially presenting with psychiatric symptoms developed myoclonus and was admitted 1 month later to the ICU with a suspected nonconvulsive status epilepticus and respiratory insufficiency, probably due to extensive antiepileptic drug therapy. Typical MRI and EEG findings and a positive 14-3-3 protein led to the diagnosis of sCJD. All treatments were terminated, and autopsy confirmed sCJD.<jats:italic>Conclusions<\/jats:italic>. Clinical signs combined with MRI, EEG, and 14-3-3 and\/or tau protein determination might be sufficient to diagnose or exclude sCJD and may therefore prevent the application of unnecessary diagnostic tests.<\/jats:p>","DOI":"10.1155\/2013\/630141","type":"journal-article","created":{"date-parts":[[2013,4,4]],"date-time":"2013-04-04T18:28:44Z","timestamp":1365100124000},"page":"1-4","source":"Crossref","is-referenced-by-count":2,"title":["Diagnosing Sporadic Creutzfeldt-Jakob Disease in a Patient with a Suspected Status Epilepticus in the Intensive Care Unit"],"prefix":"10.1155","volume":"2013","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9923-0866","authenticated-orcid":true,"given":"Harm J.","family":"van der Horn","sequence":"first","affiliation":[{"name":"University Medical Centre Groningen, GN, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter H.","family":"Egbers","sequence":"additional","affiliation":[{"name":"Department of Intensive 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