{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:03:09Z","timestamp":1740164589622,"version":"3.37.3"},"reference-count":22,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Hematology"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>Vitamin B<jats:sub>12<\/jats:sub>deficiency results in neuropsychiatric, hematologic, gynecologic, cardiovascular, and cutaneous manifestations. It is seen most commonly in the elderly, malabsorption diseases\u2009\u2009(&gt;60% of all cases), vegans, and vegetarians. Manifestations of pernicious anemia may be similar to Addison disease and may lead to a misdiagnosis. Herein, we report two cases of vitamin B<jats:sub>12<\/jats:sub>deficiency in which clinical features shared many similarities with Addison disease. Both patients presented with progressive darkening of hands and postural hypotension that reversed with replenishment of vitamin B<jats:sub>12<\/jats:sub>. Vitamin B<jats:sub>12<\/jats:sub>deficiency should be considered in patients presenting with skin lesions especially with other coexisting autoimmune diseases.<\/jats:p>","DOI":"10.1155\/2013\/680459","type":"journal-article","created":{"date-parts":[[2013,6,11]],"date-time":"2013-06-11T21:01:42Z","timestamp":1370984502000},"page":"1-5","source":"Crossref","is-referenced-by-count":3,"title":["A Reversible Cause of Skin Hyperpigmentation and Postural Hypotension"],"prefix":"10.1155","volume":"2013","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6064-6140","authenticated-orcid":true,"given":"Rabia","family":"Cherqaoui","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Howard University, Washington, DC 20060, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehreen","family":"Husain","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Howard University, Washington, DC 20060, 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