{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,6]],"date-time":"2024-07-06T07:50:27Z","timestamp":1720252227520},"reference-count":9,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Pediatrics"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>We present a case of a seven-year-old immunocompetent female patient who developed systemic symptoms mimicking an autoimmune rather than an infectious disease. The patient presented with rash, biquotidian fever, night sweats, and arthralgias. There was no antecedent history of cat contact. Investigations showed increased inflammatory markers, leukocytosis, thrombocytosis, hypercalcemia, and raised angiotensin-converting enzyme. Interferon-gamma releasing assay for tuberculosis infection was negative. Abdominal imaging demonstrated multifocal lesions of the liver and spleen (later proved to be granulomata), chest X-ray showed enlarged hilar lymph nodes, and ophthalmology review revealed uveitis. Clinical, laboratory, and imaging features pointed towards sarcoidosis. Subsequently, raised titers (IgM 1 : 32, IgG 1 : 256) against<jats:italic>Bartonella<\/jats:italic>confirmed the diagnosis of<jats:italic>B. henselae<\/jats:italic>infection. She was treated with gentamycin followed by ciprofloxacin; repeat investigations showed complete resolution of findings. The presence of hepatic and splenic lesions in children with bartonellosis is well documented. Our case, however, exhibited certain unusual findings such as the coexistence of acute ocular and systemic involvement in an immunocompetent host. Serological testing is an inexpensive and effective way to diagnose bartonellosis in immunocompetent patients; we suggest that bartonella serology is included in the baseline tests performed on children with prolonged fever even in the absence of contact with cats in countries where bartonellosis is prevalent.<\/jats:p>","DOI":"10.1155\/2013\/726826","type":"journal-article","created":{"date-parts":[[2013,1,17]],"date-time":"2013-01-17T21:02:54Z","timestamp":1358456574000},"page":"1-4","source":"Crossref","is-referenced-by-count":5,"title":["<i>Bartonella henselae<\/i>Infection: An Uncommon Mimicker of Autoimmune Disease"],"prefix":"10.1155","volume":"2013","author":[{"given":"Despoina N.","family":"Maritsi","sequence":"first","affiliation":[{"name":"Second Department of Academic Pediatrics, Athens Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece"},{"name":"Department of Paediatrics, MITERA Childrens\u07e3 Hospital, 15237 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diagoras","family":"Zarganis","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, MITERA Childrens\u07e3 Hospital, 15237 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zoi","family":"Metaxa","sequence":"additional","affiliation":[{"name":"Second Department of Academic Pediatrics, Athens Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgia","family":"Papaioannou","sequence":"additional","affiliation":[{"name":"Department of Pediatric Radiology, MITERA Childrens\u07e3 Hospital, 15237 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Vartzelis","sequence":"additional","affiliation":[{"name":"Second Department of Academic Pediatrics, Athens Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece"},{"name":"Department of Paediatrics, MITERA Childrens\u07e3 Hospital, 15237 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"issue":"1","key":"1","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1086\/516256","volume":"26","year":"1998","journal-title":"Clinical Infectious Diseases"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199702000-00002"},{"issue":"4","key":"3","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1128\/JCM.37.4.993-997.1999","volume":"37","year":"1999","journal-title":"Journal of Clinical Microbiology"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1086\/324162"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1007\/s11908-000-0026-8"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S20157"},{"issue":"5","key":"7","doi-asserted-by":"crossref","first-page":"e43","DOI":"10.1086\/427881","volume":"40","year":"2005","journal-title":"Clinical Infectious Diseases"},{"issue":"5","key":"8","first-page":"587","volume":"82","year":"1998","journal-title":"British Journal of Ophthalmology"},{"issue":"4","key":"9","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1086\/515197","volume":"28","year":"1999","journal-title":"Clinical Infectious Diseases"}],"container-title":["Case Reports in Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripe\/2013\/726826.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripe\/2013\/726826.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripe\/2013\/726826.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,20]],"date-time":"2020-07-20T16:32:31Z","timestamp":1595262751000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/cripe\/2013\/726826\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":9,"alternative-id":["726826","726826"],"URL":"https:\/\/doi.org\/10.1155\/2013\/726826","relation":{},"ISSN":["2090-6803","2090-6811"],"issn-type":[{"value":"2090-6803","type":"print"},{"value":"2090-6811","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}