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Two normal human male subjects were sequentially imaged with PET and tagged MRI imaging. Strain predictions were made for systolic contraction using warping analyses of the PET images and HARP based strain analyses of the MRI images. Coefficient of determination<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mrow><mml:mrow><mml:msup><mml:mi>R<\/mml:mi><mml:mn>2<\/mml:mn><\/mml:msup><\/mml:mrow><\/mml:mrow><\/mml:mrow><\/mml:math>values were computed for the comparison of circumferential and radial strain predictions produced by each methodology. There was good correspondence between the methodologies, with<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mrow><mml:mrow><mml:msup><mml:mi>R<\/mml:mi><mml:mn>2<\/mml:mn><\/mml:msup><\/mml:mrow><\/mml:mrow><\/mml:mrow><\/mml:math>values of 0.78 for the radial strains of both hearts and from an<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mrow><mml:msup><mml:mi>R<\/mml:mi><mml:mn>2<\/mml:mn><\/mml:msup><mml:mo>=<\/mml:mo><mml:mn>0.81<\/mml:mn><\/mml:mrow><\/mml:math>and<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mrow><mml:msup><mml:mi>R<\/mml:mi><mml:mn>2<\/mml:mn><\/mml:msup><mml:mo>=<\/mml:mo><mml:mn>0.83<\/mml:mn><\/mml:mrow><\/mml:math>for the circumferential strains. The strain predictions were not statistically different<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mrow><mml:mrow><mml:mo stretchy=\"false\">(<\/mml:mo><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>\u2264<\/mml:mo><mml:mn>0.01<\/mml:mn><\/mml:mrow><mml:mo stretchy=\"false\">)<\/mml:mo><\/mml:mrow><\/mml:mrow><\/mml:math>. A series of sensitivity results indicated that the methodology was relatively insensitive to alterations in image intensity, random image noise, and alterations in fiber structure. This study demonstrated that warping was able to provide strain predictions of systolic contraction of the LV consistent with those provided by tagged MRI Warping.<\/jats:p>","DOI":"10.1155\/2013\/728624","type":"journal-article","created":{"date-parts":[[2013,6,13]],"date-time":"2013-06-13T17:04:45Z","timestamp":1371143085000},"page":"1-14","source":"Crossref","is-referenced-by-count":7,"title":["A Comparison of Hyperelastic Warping of PET Images with Tagged MRI for the Analysis of Cardiac Deformation"],"prefix":"10.1155","volume":"2013","author":[{"given":"Alexander I.","family":"Veress","sequence":"first","affiliation":[{"name":"Department of Mechanical Engineering, University of Washington, Seattle Washington, Stevens Way, P.O. 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