{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T09:58:54Z","timestamp":1756461534436},"reference-count":19,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>Tracheobronchomalacia (TBM) is defined as the condition where the airway lumen narrows more than 50 percent. The acquired TBM usually occurs in adults; however, the prevalence of TBM in asthma is unknown. We report two cases of severe asthma in elderly patients that could not be controlled with higher medication use. Case 1 was a 70-year-old woman with sever persistent asthma for 10 years, presented with uncontrolled symptoms for 4 months. A CT of the chest showed collapse of the trachea at the posterior wall. Case 2 involved a 72-year-old woman with partly controlled asthma presenting with uncontrolled symptoms for 3 months. A CT of the chest showed normal distal tracheal anteroposterior diameter. However, bronchoscopy showed bronchomalacia at the right and left bronchus of the lower lungs. Patients who have severe asthma, despite adequate treatment with medication, should be further investigated to exclude other diseases that have clinical features similar to asthma such as tracheobronchomalacia, particularly in the elderly.<\/jats:p>","DOI":"10.1155\/2013\/735058","type":"journal-article","created":{"date-parts":[[2013,5,13]],"date-time":"2013-05-13T21:04:19Z","timestamp":1368479059000},"page":"1-4","source":"Crossref","is-referenced-by-count":6,"title":["Refractory Asthma Treatment Is Complicated by Tracheobronchomalacia: Case Reports and Review of the Literature"],"prefix":"10.1155","volume":"2013","author":[{"given":"Sawad","family":"Boonpiyathad","sequence":"first","affiliation":[{"name":"Division of Allergy and Clinical Immunology, Department of Medicine, Phramongkutklao Hospital, Bangkok 10400, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atik","family":"Sangasapaviliya","sequence":"additional","affiliation":[{"name":"Division of Allergy and Clinical Immunology, Department of Medicine, Phramongkutklao Hospital, Bangkok 10400, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"issue":"6","key":"1","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1164\/ajrccm.162.6.ats9-00","volume":"162","year":"2000","journal-title":"The American Journal of Respiratory and Critical Care Medicine"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2010.07.019"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1097\/MCP.0b013e328321832d"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.2165\/00151829-200605020-00004"},{"issue":"2","key":"5","doi-asserted-by":"crossref","first-page":"340","DOI":"10.4187\/respcare.01866","volume":"58","year":"2013","journal-title":"Respiratory Care"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1378\/chest.127.3.984"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/S1076-6332(03)80117-4"},{"key":"8","first-page":"37","volume":"5","year":"2011","journal-title":"Clinical Medicine Insights: Circulation, Respiratory and Pulmonary Medicine"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-2559"},{"key":"10","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1177\/000348946307200415","volume":"72","year":"1963","journal-title":"Annals of Otology, Rhinology, and Laryngology"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2007.01094.x"},{"issue":"6","key":"12","first-page":"350","volume":"9","year":"1977","journal-title":"Annals of Clinical Research"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06-2556"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2009.02289.x"},{"issue":"5","key":"15","first-page":"412","volume":"21","year":"2011","journal-title":"Journal of Investigational Allergology and Clinical Immunology"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.rcl.2008.11.007"},{"issue":"5","key":"17","first-page":"812","volume":"126","year":"1982","journal-title":"The American Review of Respiratory Disease"},{"issue":"2","key":"18","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1164\/ajrccm\/147.2.457","volume":"147","year":"1993","journal-title":"The American Review of Respiratory Disease"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2006.00862.x"}],"container-title":["Case Reports in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2013\/735058.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2013\/735058.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2013\/735058.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T18:19:28Z","timestamp":1688235568000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crim\/2013\/735058\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":19,"alternative-id":["735058","735058"],"URL":"https:\/\/doi.org\/10.1155\/2013\/735058","relation":{},"ISSN":["1687-9627","1687-9635"],"issn-type":[{"value":"1687-9627","type":"print"},{"value":"1687-9635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}