{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:47:00Z","timestamp":1753886820071,"version":"3.41.2"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,9,30]],"date-time":"2013-09-30T00:00:00Z","timestamp":1380499200000},"content-version":"vor","delay-in-days":272,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Scientific World Journal"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Periprosthetic infections remain a devastating problem in\n\t\t\t\t\t the field of joint arthroplasty. In the following study, the results of a two\u2010stage treatment\n\t\t\t\t\t  protocol for chronic periprosthetic infections using an intraoperatively molded cement\n\t\t\t\t\t   prosthesis\u2010like spacer (CPLS) are presented. <jats:italic>Methods<\/jats:italic>. Seventy\u2010five patients\n\t\t\t\t\t    with chronically infected knee prosthesis received a two\u2010stage revision procedure with the newly\n\t\t\t\t\t     developed CPLS between June 2006 and June 2011. Based on the microorganism involved,\n\t\t\t\t\t      patients were grouped into either easy to treat (ETT) or difficult to treat (DTT) and treated accordingly. \n\t\t\t\t\t       Range of motion (ROM) and the knee society score (KSS) were utilized for functional\n\t\t\t\t\t        assessment. <jats:italic>Results<\/jats:italic>. Mean duration of the CPLS implant in the DTT\n\t\t\t\t\t         group was 3.6 months (range 3\u20135 months) and in the ETT group 1.3 months\n\t\t\t\t\t          (range 0.7\u20132.5 months). Reinfection rates of the final prosthesis were\n\t\t\t\t\t           9.6% in the ETT and 8.3% in the DTT group with no significant difference between both groups regarding ROM or KSS (<jats:italic>P<\/jats:italic> = 0.87, 0.64, resp.). <jats:italic>Conclusion<\/jats:italic>. The\n\t\t\t\t\t results show that ETT patients do not necessitate the same treatment protocol as\n\t\t\t\t\t  DTT patients to achieve the same goal, emphasizing the need to differentiate between\n\t\t\t\t\t   therapeutic regimes. We also highlight the feasibility of CLPS in two\u2010stage protocols.<\/jats:p>","DOI":"10.1155\/2013\/763434","type":"journal-article","created":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T03:27:24Z","timestamp":1380598044000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The Cement Prosthesis\u2010Like Spacer: An Intermediate Halt on the Road to Healing"],"prefix":"10.1155","volume":"2013","author":[{"given":"Sufian S.","family":"Ahmad","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim","family":"Huber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitrios S.","family":"Evangelopoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Kleer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hendrik","family":"Kohlhof","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Sch\u00e4r","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Eggli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandro","family":"Kohl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,9,30]]},"reference":[{"key":"e_1_2_6_1_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780300811"},{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/454873"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2007.06.014"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2007.12.013"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2010.01.013"},{"key":"e_1_2_6_6_2","first-page":"169","article-title":"Treatment of infected total knee arthroplasty","author":"Whiteside L. 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