{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T18:41:00Z","timestamp":1791484860346,"version":"4.3.4"},"reference-count":17,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Rheumatology"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>Rheumatoid arthritis (RA) is considered as a connective tissue disease while ankylosing spondylitis (AS) is a prototype of spondyloarthritis. These diseases are seen concomitantly only very rarely. Also, rituximab has proven efficacy in the treatment of RA while its role in the treatment of AS is unclear. In this presentation, the concomitant presence of RA and AS in a 43-year-old male patient as well as the efficacy and safety of rituximab is discussed. Rituximab was given due to lack of response to treatment with anti-TNF-alpha. Evaluations made at the 6th and 12th months of treatment showed complete response for RA and partial response for AS.<\/jats:p>","DOI":"10.1155\/2013\/792526","type":"journal-article","created":{"date-parts":[[2013,11,12]],"date-time":"2013-11-12T16:11:28Z","timestamp":1384272688000},"page":"1-4","source":"Crossref","is-referenced-by-count":2,"title":["The Efficacy and Safety of Rituximab in a Patient with Rheumatoid Spondylitis"],"prefix":"10.1155","volume":"2013","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8270-640X","authenticated-orcid":true,"given":"\u015eenol","family":"Kobak","sequence":"first","affiliation":[{"name":"Department of Rheumatology, Faculty of Medicine, \u015eifa University, Bornova, 35100 Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet","family":"Karaarslan","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Faculty of Medicine, \u015eifa University, Bornova, 35100 Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahrettin","family":"Oksel","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Faculty of Medicine, Ege University, 35100 Izmir, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60635-7"},{"key":"2","volume-title":"Rheumatoid arthritis: clinical features and systemic involvement","volume":"1","year":"1992"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2005.041137"},{"key":"4","volume":"52, article 1917","year":"2005","journal-title":"Arthritis and Rheumatism"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2007.079095"},{"issue":"10","key":"6","first-page":"2017","volume":"35","year":"2008","journal-title":"Journal of Rheumatology"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1517\/14656566.5.7.1497"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780380407"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1136\/ard.59.2.135"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1186\/ar2035"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1002\/art.27383"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ken362"},{"key":"13","first-page":"626","volume":"68","year":"2009","journal-title":"Annals of the Rheumatic Diseases"},{"key":"14","first-page":"626","volume":"67","year":"2008","journal-title":"Annals of the Rheumatic Diseases"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2008.01.023"},{"key":"16","first-page":"317","volume":"67","year":"2008","journal-title":"Annals of the Rheumatic Diseases"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e3282f5e08d"}],"container-title":["Case Reports in Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crirh\/2013\/792526.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crirh\/2013\/792526.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crirh\/2013\/792526.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,18]],"date-time":"2016-08-18T22:46:53Z","timestamp":1471560413000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crirh\/2013\/792526\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":17,"alternative-id":["792526","792526"],"URL":"https:\/\/doi.org\/10.1155\/2013\/792526","relation":{},"ISSN":["2090-6889","2090-6897"],"issn-type":[{"value":"2090-6889","type":"print"},{"value":"2090-6897","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}