{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:07:54Z","timestamp":1787098074307,"version":"build-2736575974"},"reference-count":74,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Surgical Oncology"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>Breast-conserving surgery (BCS) is the treatment of choice for early breast cancer. The adequacy of surgical margins (SM) is a crucial issue for adjusting the volume of excision and for avoiding local recurrences, although the precise definition of an adequate margins width remains controversial. Moreover, other factors such as the biological behaviour of the tumor and subsequent proper systemic therapies may influence the local recurrence rate (LRR). However, a successful BCS requires preoperative localization techniques or margin assessment techniques. Carbon marking, wire-guided, biopsy clips, radio-guided, ultrasound-guided, frozen section analysis, imprint cytology, and cavity shave margins are commonly used, but from the literature review, no single technique proved to be better among the various ones. Thus, an association of two or more methods could result in a decrease in rates of involved margins. Each institute should adopt its most congenial techniques, based on the senologic equipe experience, skills, and technologies.<\/jats:p>","DOI":"10.1155\/2013\/793819","type":"journal-article","created":{"date-parts":[[2013,8,5]],"date-time":"2013-08-05T21:22:37Z","timestamp":1375737757000},"page":"1-9","source":"Crossref","is-referenced-by-count":29,"title":["Preoperative Localization and Surgical Margins in Conservative Breast Surgery"],"prefix":"10.1155","volume":"2013","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6469-4086","authenticated-orcid":true,"given":"F.","family":"Corsi","sequence":"first","affiliation":[{"name":"Surgery Division, Department of Clinical Sciences, L. Sacco Hospital, University of Milan, Via G.B. Grassi 74, 20157 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5502-3937","authenticated-orcid":true,"given":"L.","family":"Sorrentino","sequence":"additional","affiliation":[{"name":"Surgery Division, Department of Clinical Sciences, L. Sacco Hospital, University of Milan, Via G.B. Grassi 74, 20157 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7917-0437","authenticated-orcid":true,"given":"D.","family":"Bossi","sequence":"additional","affiliation":[{"name":"Surgery Division, Department of Clinical Sciences, L. Sacco Hospital, University of Milan, Via G.B. Grassi 74, 20157 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8016-4624","authenticated-orcid":true,"given":"A.","family":"Sartani","sequence":"additional","affiliation":[{"name":"Surgery Division, Department of Clinical Sciences, L. Sacco Hospital, University of Milan, Via G.B. Grassi 74, 20157 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7702-8226","authenticated-orcid":true,"given":"D.","family":"Foschi","sequence":"additional","affiliation":[{"name":"Surgery Division, Department of Clinical Sciences, L. Sacco Hospital, University of Milan, Via G.B. Grassi 74, 20157 Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(02)01012-7"},{"issue":"3","key":"2","first-page":"161","volume":"8","year":"1992","journal-title":"Seminars in Surgical Oncology"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa022152"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa020989"},{"key":"5","first-page":"1921","volume":"9","year":"1996","journal-title":"Cancer"},{"key":"6","doi-asserted-by":"crossref","first-page":"1746","DOI":"10.1002\/1097-0142(19940915)74:6<1746::AID-CNCR2820740617>3.0.CO;2-Y","volume":"74","year":"1994","journal-title":"Cancer"},{"issue":"8","key":"7","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1200\/JCO.2000.18.8.1668","volume":"18","year":"2000","journal-title":"Journal of Clinical Oncology"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(98)00519-7"},{"issue":"5","key":"9","first-page":"1053","volume":"9","year":"2002","journal-title":"Oncology Reports"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/BF02967655"},{"issue":"6","key":"11","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1097\/00130404-200311000-00003","volume":"9","year":"2003","journal-title":"Cancer Journal"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(03)01460-3"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.2325\/jbcs.12.91"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2007.11.029"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2010.07.043"},{"key":"16","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1056\/NEJMsb1202521","volume":"367","year":"2012","journal-title":"The New England Journal of Medicine"},{"key":"17","volume":"345","year":"2012","journal-title":"British Medical Journal"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/88.21.1529"},{"key":"19","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1200\/JCO.1996.14.7.1982","volume":"14","year":"1996","journal-title":"Journal of Clinical Oncology"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/S1072-7515(97)00024-0"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-008-0054-4"},{"key":"22","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.amjsurg.2012.03.007","volume":"204","year":"2012","journal-title":"The American Journal of Surgery"},{"key":"23","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1007\/s10549-012-2124-3","volume":"134","year":"2012","journal-title":"Breast Cancer Research and Treatment"},{"issue":"3","key":"24","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1001\/archsurg.1996.01430150079015","volume":"131","year":"1996","journal-title":"Archives of Surgery"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199905133401902"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181b5931e"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1002\/jso.1041"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djs142"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1002\/jso.21700"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(05)01765-1"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1097\/01.PRS.0000046491.87997.40"},{"key":"32","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/tbj.12047","volume":"19","year":"2013","journal-title":"Breast Journal"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0b013e3182605598"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1016\/S0748-7983(05)80067-8"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2007.8.4.295"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1080\/02841850802452075"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9776(03)00105-X"},{"issue":"1","key":"38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2214\/ajr.152.1.1","volume":"152","year":"1989","journal-title":"American Journal of Roentgenology"},{"issue":"3","key":"39","doi-asserted-by":"crossref","first-page":"489","DOI":"10.2214\/ajr.143.3.489","volume":"143","year":"1984","journal-title":"American Journal of Roentgenology"},{"issue":"3","key":"40","first-page":"614","volume":"151","year":"1988","journal-title":"American Journal of Roentgenology"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1002\/jso.23016"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2010.12.006"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2011.12.003"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-011-1847-x"},{"issue":"6","key":"45","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.2214\/ajr.181.6.1811685","volume":"181","year":"2003","journal-title":"American Journal of Roentgenology"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4741.2003.09319.x"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2009.10.017"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2005.06.027"},{"key":"49","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(03)00277-0"},{"issue":"1","key":"50","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/S0959-8049(97)00376-6","volume":"34","year":"1998","journal-title":"European Journal of Cancer"},{"key":"51","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-007-9452-2"},{"key":"52","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/27639166"},{"key":"53","doi-asserted-by":"publisher","DOI":"10.1002\/jso.20880"},{"issue":"3","key":"54","doi-asserted-by":"crossref","first-page":"569","DOI":"10.2214\/ajr.163.3.8079846","volume":"163","year":"1994","journal-title":"American Journal of Roentgenology"},{"key":"55","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-004-7554-6"},{"key":"56","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9260(05)81973-7"},{"key":"57","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-200105000-00011"},{"key":"58","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-006-9076-y"},{"key":"59","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1002\/(SICI)1096-9098(199910)72:2<72::AID-JSO6>3.0.CO;2-M","volume":"72","year":"1999","journal-title":"Journal of Surgical Oncology"},{"key":"60","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/S1470-2045(12)70527-2","volume":"14","year":"2013","journal-title":"The Lancet Oncology"},{"key":"61","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-012-2492-2"},{"issue":"8","key":"62","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1007\/BF02303749","volume":"4","year":"1997","journal-title":"Annals of Surgical Oncology"},{"issue":"10","key":"63","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1177\/000313480707301009","volume":"73","year":"2007","journal-title":"American Surgeon"},{"key":"64","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-010-1420-6"},{"key":"65","doi-asserted-by":"publisher","DOI":"10.1007\/s12282-013-0473-3"},{"key":"66","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4741.2008.00649.x"},{"key":"67","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-011-1982-y"},{"key":"68","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa052122"},{"key":"69","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181f08f32"},{"key":"70","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-011-1486-2"},{"key":"71","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1056\/NEJMc1209255","volume":"367","year":"2012","journal-title":"The New England Journal of Medicine"},{"key":"72","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdg452"},{"key":"73","doi-asserted-by":"publisher","DOI":"10.3332\/ecancer.2013.299"},{"issue":"5","key":"75","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.2214\/ajr.175.5.1751353","volume":"175","year":"2000","journal-title":"American Journal of Roentgenology"}],"container-title":["International Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijso\/2013\/793819.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijso\/2013\/793819.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijso\/2013\/793819.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,3]],"date-time":"2022-03-03T00:23:15Z","timestamp":1646266995000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/ijso\/2013\/793819\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":74,"alternative-id":["793819","793819"],"URL":"https:\/\/doi.org\/10.1155\/2013\/793819","relation":{},"ISSN":["2090-1402","2090-1410"],"issn-type":[{"value":"2090-1402","type":"print"},{"value":"2090-1410","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}