{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T23:05:32Z","timestamp":1778713532094,"version":"3.51.4"},"reference-count":38,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Disease Markers"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p><jats:italic>Introduction<\/jats:italic>. This study was designed to correlate the serum and gingival crevicular fluid (GCF) levels of progranulin (PGRN) and high sensitivity C-reactive protein (hs CRP) in chronic periodontitis and type 2 diabetes mellitus (DM).<jats:italic>Design<\/jats:italic>. PGRN and hs CRP levels were estimated in 3 groups: healthy, chronic periodontitis, and type 2 DM with chronic periodontitis.<jats:italic>Results<\/jats:italic>. The mean PGRN and hs CRP concentrations in serum and GCF were the highest for group 3 followed by group 2 and the least in group 1.<jats:italic>Conclusion<\/jats:italic>. PGRN and hs CRP may be biomarkers of the inflammatory response in type 2 DM and chronic periodontitis.<\/jats:p>","DOI":"10.1155\/2013\/803240","type":"journal-article","created":{"date-parts":[[2013,9,26]],"date-time":"2013-09-26T21:12:06Z","timestamp":1380229926000},"page":"389-394","source":"Crossref","is-referenced-by-count":13,"title":["Crevicular Fluid and Serum Concentrations of Progranulin and High Sensitivity CRP in Chronic Periodontitis and Type 2 Diabetes"],"prefix":"10.1155","volume":"35","author":[{"given":"N.","family":"Priyanka","sequence":"first","affiliation":[{"name":"Department of Periodontics, Government Dental College and Research Institute, Bangalore, Karnataka 560002, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minal","family":"Kumari","sequence":"additional","affiliation":[{"name":"Department of Periodontics, Government Dental College and Research Institute, Bangalore, Karnataka 560002, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nitish","family":"Kalra","sequence":"additional","affiliation":[{"name":"Department of Periodontics, Government Dental College and Research Institute, Bangalore, Karnataka 560002, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Arjun","sequence":"additional","affiliation":[{"name":"Bangalore Medical College and Research Institute, Bangalore, Karnataka 560002, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Savitha B.","family":"Naik","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Government Dental College and Research Institute, Bangalore, Karnataka 560002, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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