{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T06:33:27Z","timestamp":1774506807725,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Oncological Medicine"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>Atypical Teratoid Rhabdoid Tumor (ATRT) is a rare malignant intracranial neoplasm more commonly diagnosed in young children. The authors report the case of an 11-year-old boy with a long standing history of slowly progressive weight loss, fatigue, and weakness over 1.5 years whose magnetic resonance imaging revealed a large heterogeneous enhancing dorsally exophytic lower brainstem mass. Examination revealed extreme cachexia, gaze-evoked nystagmus, dysphagia, dysarthria, bilateral dysmetria, and global weakness without ambulation. The protracted history and neuroimaging features were most suggestive of a low grade glioma. However, pathology revealed a hypercellular tumor with large hyperchromatic nucleoli and loss of INI-1 staining on immunohistochemistry consistent with a diagnosis of an ATRT. The child died shortly after surgery due to complications from his brainstem infiltrative disease. This case illustrates the diverse presentation of ATRT in childhood that can clinically and radiographically mimic that of low grade glioma.<\/jats:p>","DOI":"10.1155\/2013\/815923","type":"journal-article","created":{"date-parts":[[2013,5,27]],"date-time":"2013-05-27T17:01:46Z","timestamp":1369674106000},"page":"1-4","source":"Crossref","is-referenced-by-count":2,"title":["Atypical Presentation of Atypical Teratoid Rhabdoid Tumor in a Child"],"prefix":"10.1155","volume":"2013","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4563-2525","authenticated-orcid":true,"given":"Y. T.","family":"Udaka","sequence":"first","affiliation":[{"name":"The Department of Pediatrics, University of California, San Diego and Rady Children\u2019s Hospital, 3020 Children\u2019s Way, San Diego, CA 92123, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Shayan","sequence":"additional","affiliation":[{"name":"The Department of Pediatrics, University of California, San Diego and Rady Children\u2019s Hospital, 3020 Children\u2019s Way, San Diego, CA 92123, USA"},{"name":"The Department of Pathology, University of California, San Diego and Rady Children\u2019s Hospital, 3020 Children\u2019s Way, San Diego, CA 92123, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3432-2564","authenticated-orcid":true,"given":"N. A.","family":"Chuang","sequence":"additional","affiliation":[{"name":"The Department of Radiology, University of California, San Diego and Rady Children\u2019s Hospital, 3020 Children\u2019s Way, San Diego, CA 92123, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. R.","family":"Crawford","sequence":"additional","affiliation":[{"name":"The Department of Pediatrics, University of California, San Diego and Rady Children\u2019s Hospital, 3020 Children\u2019s Way, San Diego, CA 92123, USA"},{"name":"The Department of Neurosciences, University of California, San Diego and Rady Children\u2019s Hospital, 3020 Children\u2019s Way, San Diego, CA 92123, USA"},{"name":"University of California, San Diego, Division of Child Neurology, Rady Children\u2019s Hospital, 8010 Frost Street Suite 400, San Diego, CA 92123, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"1","key":"2","first-page":"E11","volume":"20","year":"2006","journal-title":"Neurosurgical Focus"},{"key":"3","volume":"2, article 114","year":"2012","journal-title":"Frontiers in Oncology"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1007\/s00292-002-0530-8"},{"issue":"3","key":"5","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1093\/jnen\/61.3.215","volume":"61","year":"2002","journal-title":"Journal of Neuropathology and Experimental Neurology"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.22831"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.07.073"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1007\/BF01052653"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1023\/A:1010683416555"},{"issue":"5","key":"10","first-page":"962","volume":"27","year":"2006","journal-title":"The American Journal of Neuroradiology"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-005-0037-6"},{"issue":"3","key":"12","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/s00247-012-2530-z","volume":"43","year":"2013","journal-title":"Pediatric Radiology"},{"issue":"1","key":"13","doi-asserted-by":"crossref","first-page":"56","DOI":"10.3171\/jns.1996.85.1.0056","volume":"85","year":"1996","journal-title":"Journal of Neurosurgery"}],"container-title":["Case Reports in Oncological Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crionm\/2013\/815923.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crionm\/2013\/815923.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crionm\/2013\/815923.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T09:42:06Z","timestamp":1498038126000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crionm\/2013\/815923\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":12,"alternative-id":["815923","815923"],"URL":"https:\/\/doi.org\/10.1155\/2013\/815923","relation":{},"ISSN":["2090-6706","2090-6714"],"issn-type":[{"value":"2090-6706","type":"print"},{"value":"2090-6714","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}