{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T13:06:00Z","timestamp":1769605560376,"version":"3.49.0"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Obstetrics and Gynecology"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p>The primary small cell carcinoma of the vagina is rare, and it is a highly aggressive malignancy with no consensus regarding the treatment of this tumor. The survival rate for patients treated in the early stages is around two years. We related the case report of a patient of 41 years with a vegetative and necrotic lesion in left vaginal wall, in middle and upper third, and involvement of parametrium in its proximal third and medium third. A biopsy showed a small cell undifferentiated carcinoma composed of epithelial cells with round nuclei, oval or elongated, hyperchromatic nuclei, with little distinct nucleoli, and scarce cytoplasm. Immunohistochemistry showed positivity for AE1\/AE3, CD57, and chromogranin A. The patient received 6 cycles of chemotherapy with cisplatin and etoposide and radiotherapy, achieving complete response, with complete regression of the lesion. The patient had no sign of tumor recurrence and locoregional or distant metastases after 5 months of followup.<\/jats:p>","DOI":"10.1155\/2013\/827037","type":"journal-article","created":{"date-parts":[[2013,6,26]],"date-time":"2013-06-26T17:30:12Z","timestamp":1372267812000},"page":"1-4","source":"Crossref","is-referenced-by-count":7,"title":["Primary Small Cell Carcinoma of the Vagina"],"prefix":"10.1155","volume":"2013","author":[{"given":"Rafael","family":"Oliveira","sequence":"first","affiliation":[{"name":"Research Institute of Oncology (IPON), Discipline of Gynecology and Obstetrics, Federal University of Tri\u00e2ngulo Mineiro (UFTM), Avenida Get\u00falio Guarit\u00e1 214, 38025-440 Uberaba, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayra Coelho","family":"B\u00f3coli","sequence":"additional","affiliation":[{"name":"Research Institute of Oncology (IPON), Discipline of Gynecology and Obstetrics, Federal University of Tri\u00e2ngulo Mineiro (UFTM), Avenida Get\u00falio Guarit\u00e1 214, 38025-440 Uberaba, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o Carlos","family":"Saldanha","sequence":"additional","affiliation":[{"name":"Discipline of Surgical Pathology, Federal University of Tri\u00e2ngulo Mineiro (UFTM), Uberaba, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4014-1345","authenticated-orcid":true,"given":"Eddie Fernando Candido","family":"Murta","sequence":"additional","affiliation":[{"name":"Research Institute of Oncology (IPON), Discipline of Gynecology and Obstetrics, Federal University of Tri\u00e2ngulo Mineiro (UFTM), Avenida Get\u00falio Guarit\u00e1 214, 38025-440 Uberaba, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6591-7619","authenticated-orcid":true,"given":"Rosekeila Sim\u00f5es","family":"Nomelini","sequence":"additional","affiliation":[{"name":"Research Institute of Oncology (IPON), Discipline of Gynecology and Obstetrics, Federal University of Tri\u00e2ngulo Mineiro (UFTM), Avenida Get\u00falio Guarit\u00e1 214, 38025-440 Uberaba, MG, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"4","key":"1","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1002\/1097-0142(19850215)55:4<892::AID-CNCR2820550430>3.0.CO;2-N","volume":"55","year":"1985","journal-title":"Cancer"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-004-0630-1"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1097\/CCO.0b013e3283565ed6"},{"issue":"10","key":"4","doi-asserted-by":"crossref","first-page":"2484","DOI":"10.1002\/1097-0142(19921115)70:10<2484::AID-CNCR2820701015>3.0.CO;2-O","volume":"70","year":"1992","journal-title":"Cancer"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-8258(02)00153-1"},{"issue":"4","key":"6","first-page":"185","volume":"10","year":"1972","journal-title":"Patologia"},{"issue":"1","key":"7","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1097\/00004347-198403010-00005","volume":"3","year":"1984","journal-title":"International Journal of Gynecological Pathology"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1673.2000.00826.x"},{"issue":"8","key":"9","doi-asserted-by":"crossref","first-page":"857","DOI":"10.5858\/2004-128-857-PSCNCO","volume":"128","year":"2004","journal-title":"Archives of Pathology and Laboratory Medicine"},{"issue":"15","key":"10","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1056\/NEJM198704093161504","volume":"316","year":"1987","journal-title":"New England Journal of Medicine"},{"issue":"5","key":"11","doi-asserted-by":"crossref","first-page":"655","DOI":"10.7326\/0003-4819-106-5-655","volume":"106","year":"1987","journal-title":"Annals of Internal Medicine"},{"issue":"3","key":"12","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1200\/JCO.1997.15.3.893","volume":"15","year":"1997","journal-title":"Journal of Clinical Oncology"},{"issue":"2","key":"13","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1200\/JCO.1993.11.2.336","volume":"11","year":"1993","journal-title":"Journal of Clinical Oncology"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199901283400403"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1998.4959"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2011.04.011"}],"container-title":["Case Reports in Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criog\/2013\/827037.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criog\/2013\/827037.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criog\/2013\/827037.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,26]],"date-time":"2022-02-26T13:33:23Z","timestamp":1645882403000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/criog\/2013\/827037\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":16,"alternative-id":["827037","827037"],"URL":"https:\/\/doi.org\/10.1155\/2013\/827037","relation":{},"ISSN":["2090-6684","2090-6692"],"issn-type":[{"value":"2090-6684","type":"print"},{"value":"2090-6692","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}