{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T03:03:08Z","timestamp":1789009388101,"version":"build-2803163510"},"reference-count":15,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,12,26]],"date-time":"2013-12-26T00:00:00Z","timestamp":1388016000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pathology Research International"],"published-print":{"date-parts":[[2013,12,26]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. To assess the level of haemoglobin A<jats:sub>2<\/jats:sub> in HIV patients on antiretroviral therapy (ART) including zidovudine with untreated HIV patients. <jats:italic>Material and Methods<\/jats:italic>. The study was a case control study. A total of 185 patients were included in the study; the case group included 125 HIV patients who were on antiretroviral therapy (ART) including zidovudine and 60 were in the control group who were not receiving ART. The high-performance liquid chromatography (HPLC) was done and hemoglobin A<jats:sub>2<\/jats:sub> level was observed; value more than 3.5% was considered significant. The Hb A<jats:sub>2<\/jats:sub> percentages of HIV patients were compared with those of control using an unpaired <jats:italic>t<\/jats:italic>-test. Results. The mean of Hb A<jats:sub>2<\/jats:sub> in case group was 3.462% (SD 0.675)  and in control group it was 2.815% (SD0.246). The higher Hb A<jats:sub>2<\/jats:sub> value was seen in significant number of treated patients than control group (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.0001<\/mml:mn><\/mml:math>). Conclusion. The clinicians, pathologists, haematologists, and genetic counsellors should be aware of effects of nutritional anaemia and ART on Hb A<jats:sub>2<\/jats:sub> to reduce the chances of misdiagnosis of <jats:italic>\u03b2<\/jats:italic>-thalassaemia especially in developing countries and for centres for antenatal screening.<\/jats:p>","DOI":"10.1155\/2013\/828214","type":"journal-article","created":{"date-parts":[[2013,12,26]],"date-time":"2013-12-26T21:01:25Z","timestamp":1388091685000},"page":"1-3","source":"Crossref","is-referenced-by-count":3,"title":["A Comparison of Hemoglobin <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:msub><mml:mrow><mml:mtext>A<\/mml:mtext><\/mml:mrow><mml:mrow><mml:mn mathvariant=\"bold\">2<\/mml:mn><\/mml:mrow><\/mml:msub><\/mml:mrow><\/mml:math> Levels in Untreated and Treated Groups of HIV Patients on ART Including Zidovudine"],"prefix":"10.1155","volume":"2013","author":[{"given":"Jitendra Singh","family":"Nigam","sequence":"first","affiliation":[{"name":"Department of Pathology, D.D.U. Hospital, Hari Nagar, New Delhi 110066, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyotsna Naresh","family":"Bharti","sequence":"additional","affiliation":[{"name":"Department of Pathology, Maulana Azad Medical College, New Delhi 110002, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinker","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Pathology, D.D.U. Hospital, Hari Nagar, New Delhi 110066, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankit","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Pathology, D.D.U. Hospital, Hari Nagar, New Delhi 110066, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","year":"2006"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2004.018697"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-3542(99)00065-0"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32810c8d16"},{"issue":"2","key":"5","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1002\/ajh.2830430203","volume":"43","year":"1993","journal-title":"American Journal of Hematology"},{"issue":"4","key":"6","first-page":"437","volume":"316","year":"1993","journal-title":"Comptes Rendus de l'Academie des Sciences. 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