{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T19:11:26Z","timestamp":1757704286202},"reference-count":27,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p><jats:italic>Purpose<\/jats:italic>. To evaluate the role of spectral-domain optical coherence tomography (SDOCT) to measure corneal thickness during accelerated corneal crosslinking (CXL).<jats:italic>Methods<\/jats:italic>. Intraoperative pachymetry was performed using SDOCT and ultrasound pachymetry (USP) in 6 eyes of 6 patients with keratoconus. Pachymetry readings were obtained at baseline, after epithelium removal and after 30 minutes of riboflavin instillation. SDOCT measurements of eyes with and without lid speculum during riboflavin instillation were compared.<jats:italic>Results<\/jats:italic>. There was no statistically significant difference in central corneal thickness (CCT) measurements between SDOCT and USP (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>P<\/mml:mi><mml:mo>&gt;<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:math>for all). A significant decrease in both CCT (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.031<\/mml:mn><\/mml:math>) and the thinnest corneal thickness (TCT) (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.031<\/mml:mn><\/mml:math>) was observed during CXL. There was a greater reduction in CCT (38 \u00b1 6%) with the use of lid speculum as compared to the no-speculum eyes (18 \u00b1 9%) (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.100<\/mml:mn><\/mml:math>). TCT was also reduced by a greater extent with the use of lid speculum (40 \u00b1 5% versus 26 \u00b1 7%;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.100<\/mml:mn><\/mml:math>).<jats:italic>Conclusion<\/jats:italic>. SDOCT can be successfully used to measure intraoperative corneal pachymetry during corneal CXL. SDOCT measurements demonstrated corneal thinning intraoperatively during CXL, which was further accentuated by the use of a lid speculum during the procedure.<\/jats:p>","DOI":"10.1155\/2013\/848363","type":"journal-article","created":{"date-parts":[[2013,7,25]],"date-time":"2013-07-25T22:20:09Z","timestamp":1374790809000},"page":"1-6","source":"Crossref","is-referenced-by-count":10,"title":["Intraoperative Pachymetry Using Spectral-Domain Optical Coherence Tomography during Accelerated Corneal Collagen Crosslinking"],"prefix":"10.1155","volume":"2013","author":[{"given":"Vanissa W. S.","family":"Chow","sequence":"first","affiliation":[{"name":"Hong Kong Eye Hospital, Hong Kong"},{"name":"Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sayantan","family":"Biswas","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria W. Y.","family":"Wong","sequence":"additional","affiliation":[{"name":"Hong Kong Eye Hospital, Hong Kong"},{"name":"Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vishal","family":"Jhanji","sequence":"additional","affiliation":[{"name":"Hong Kong Eye Hospital, Hong Kong"},{"name":"Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong"},{"name":"Department of Ophthalmology, Prince of Wales Hospital, Shatin, Hong Kong"},{"name":"Centre for Eye Research Australia, University of Melbourne, Melbourne, VIC 3002, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(03)00407-3"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2010.185868"},{"key":"3","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1136\/bjophthalmol-2012-302518","volume":"97","year":"2013","journal-title":"British Journal of Ophthalmology"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-011-9460-x"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1159\/000074071"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(03)00343-2"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2011.05.036"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20090813-12"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2011.01.016"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2009.09.018"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2010.06.002"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20100331-01"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2011.03.023"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e31821e4286"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2011.09.045"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2009.11.016"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3181e16c65"},{"key":"18","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1111\/j.1755-3768.2010.01947.x","volume":"90","year":"2012","journal-title":"Acta Ophthalmologica"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3181d00800"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2009.12.033"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2008.10.060"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2415-9-10"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20101201-01"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2011.08.030"},{"key":"25","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jtos.2013.01.002","volume":"11","year":"2013","journal-title":"The Ocular Surface"},{"key":"26","doi-asserted-by":"crossref","first-page":"776","DOI":"10.3928\/1081597X-20121011-05","volume":"28","year":"2012","journal-title":"Journal of Refractive Surgery"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1111\/vop.12029"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2013\/848363.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2013\/848363.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2013\/848363.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T16:52:06Z","timestamp":1498063926000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/bmri\/2013\/848363\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":27,"alternative-id":["848363","848363"],"URL":"https:\/\/doi.org\/10.1155\/2013\/848363","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}