{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:03:02Z","timestamp":1740164582881,"version":"3.37.3"},"reference-count":18,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Hematology"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p><jats:italic>Strongyloides stercoralis<\/jats:italic>is an intestinal nematode that causes strongyloidiasis, which affects 30 to 100 million people worldwide. Risk factors for hyperinfection and disseminated disease include immunosuppressive drug therapy, human T-lymphotropic virus-1 (HTLV-1) infection, solid organ and bone marrow transplantation, hematologic malignant diseases, hypogammaglobulinemia, and severe malnutrition and associated conditions. The diagnosis can be difficult because a single stool examination fails to detect larvae in up to 70% of the cases, and the symptoms are nonspecific. Although eosinophilia is a common finding in patients with chronic<jats:italic>Strongyloides<\/jats:italic>infection, it is an unreliable predictor of hyperinfection. Furthermore, the lack of eosinophilia while receiving immunosuppressive therapy cannot reliably exclude the underlying chronic<jats:italic>Strongyloides<\/jats:italic>infection. We report here a fatal<jats:italic>Strongyloides<\/jats:italic>hyperinfection in a patient receiving allogeneic stem cell transplantation; risk factors and outcome in this clinical setting are discussed.<\/jats:p>","DOI":"10.1155\/2013\/860976","type":"journal-article","created":{"date-parts":[[2013,7,10]],"date-time":"2013-07-10T17:02:13Z","timestamp":1373475733000},"page":"1-5","source":"Crossref","is-referenced-by-count":6,"title":["Fatal<i>Strongyloides<\/i>Hyperinfection Complicating a Gram-Negative Sepsis after Allogeneic Stem Cell Transplantation: A Case Report and Review of the Literature"],"prefix":"10.1155","volume":"2013","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2901-0897","authenticated-orcid":true,"given":"Isabel","family":"Izquierdo","sequence":"first","affiliation":[{"name":"Department of Hematology, Hospital Santa Creu i Sant Pau, C\/Mar Casasnovas 90, 08041 Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Briones","sequence":"additional","affiliation":[{"name":"Department of Hematology, Hospital Santa Creu i Sant Pau, C\/Mar Casasnovas 90, 08041 Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Lluch","sequence":"additional","affiliation":[{"name":"Department of Hematology, Hospital Arnau de Vilanova, C\/San Clemente 12, 46015 Valencia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Arqueros","sequence":"additional","affiliation":[{"name":"Department of Oncology, Hospital Santa Creu I Sant Pau, C\/Mar Casasnovas 90, 08041 Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo","family":"Martino","sequence":"additional","affiliation":[{"name":"Department of Hematology, Hospital Santa Creu i Sant Pau, C\/Mar Casasnovas 90, 08041 Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"13","doi-asserted-by":"publisher","DOI":"10.1378\/chest.128.5.3681"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2010.00517.x"},{"key":"1","doi-asserted-by":"publisher","DOI":"10.1086\/630201"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1086\/322707"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.17.1.208-217.2004"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3062.2008.00360.x"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2006.01.016"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2008.383"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-6-87"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1704309"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1K302"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1705448"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.20120"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1007\/s11908-010-0150-z"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1704104"},{"issue":"1","key":"17","doi-asserted-by":"crossref","first-page":"e5","DOI":"10.1086\/430827","volume":"41","year":"2005","journal-title":"Clinical Infectious Diseases"},{"issue":"4","key":"18","doi-asserted-by":"crossref","first-page":"453","DOI":"10.4269\/ajtmh.2003.68.453","volume":"68","year":"2003","journal-title":"The American Journal of Tropical Medicine and Hygiene"},{"issue":"3","key":"12","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1093\/clinids\/21.3.675","volume":"21","year":"1995","journal-title":"Clinical Infectious Diseases"}],"container-title":["Case Reports in Hematology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2013\/860976.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2013\/860976.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2013\/860976.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,17]],"date-time":"2019-07-17T20:54:37Z","timestamp":1563396877000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crihem\/2013\/860976\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":18,"alternative-id":["860976","860976"],"URL":"https:\/\/doi.org\/10.1155\/2013\/860976","relation":{},"ISSN":["2090-6560","2090-6579"],"issn-type":[{"type":"print","value":"2090-6560"},{"type":"electronic","value":"2090-6579"}],"subject":[],"published":{"date-parts":[[2013]]}}}