{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T13:46:28Z","timestamp":1649166388855},"reference-count":7,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Otolaryngology"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Small cell carcinoma (SmCC) in the nasal cavity and paranasal sinuses is very rare, and definitive therapies have not yet been established.<jats:italic>Methods<\/jats:italic>. Chemoradiotherapy comprised 60\u2009Gy of external radiation, with the administration of irinotecan intravenously at 60\u2009mg\/m<jats:sup>2<\/jats:sup>on days 1, 8, and 15 and cisplatin at 60\u2009mg\/m<jats:sup>2<\/jats:sup>on day 1.<jats:italic>Results<\/jats:italic>. Case 1 involved a 66-year-old woman with stage III cancer. Adverse events included decreased white blood cells, anemia, and oral mucositis, all Grade 2. The patient remained free of cancer as of 3 years and 6 months after completing the treatment. Case 2 involved a 60-year-old man with stage IV cancer. He also experienced adverse events of decreased white blood cells, anemia, and oral mucositis, all Grade 2. He died after 11 months due to metastases throughout the body.<jats:italic>Conclusions<\/jats:italic>. The results suggest that this regimen may be tolerable as a therapy for this type of carcinoma.<\/jats:p>","DOI":"10.1155\/2013\/893638","type":"journal-article","created":{"date-parts":[[2013,1,29]],"date-time":"2013-01-29T16:03:02Z","timestamp":1359475382000},"page":"1-4","source":"Crossref","is-referenced-by-count":2,"title":["Two Cases of Small Cell Cancer of the Maxillary Sinus Treated with Cisplatin plus Irinotecan and Radiotherapy"],"prefix":"10.1155","volume":"2013","author":[{"given":"Kiyoaki","family":"Tsukahara","sequence":"first","affiliation":[{"name":"Department of Head and Neck Surgery, Tokyo Medical University Hachioji Medical Center, 163 Tate-machi, Hachioji, Tokyo 193-0998, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiro","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Tokyo Medical University Hachioji Medical Center, 163 Tate-machi, Hachioji, Tokyo 193-0998, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ray","family":"Motohashi","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Tokyo Medical University Hachioji Medical Center, 163 Tate-machi, Hachioji, Tokyo 193-0998, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Tokyo Medical University Hachioji Medical Center, 163 Tate-machi, Hachioji, Tokyo 193-0998, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"issue":"6","key":"1","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1097\/00005792-198711000-00004","volume":"66","year":"1987","journal-title":"Medicine"},{"issue":"6","key":"2","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1177\/019459988309100623","volume":"91","year":"1983","journal-title":"Otolaryngology"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2005.07.006"},{"issue":"3","key":"4","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1200\/JCO.1998.16.3.1068","volume":"16","year":"1998","journal-title":"Journal of Clinical Oncology"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa003034"},{"key":"8","first-page":"67","volume":"13","year":"2005","journal-title":"Auris Nasus Larynx"},{"key":"9","first-page":"307","volume":"117","year":"1991","journal-title":"Head and Neck Surgery"}],"container-title":["Case Reports in Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criot\/2013\/893638.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criot\/2013\/893638.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criot\/2013\/893638.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,8]],"date-time":"2019-07-08T20:51:44Z","timestamp":1562619104000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/criot\/2013\/893638\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":7,"alternative-id":["893638","893638"],"URL":"https:\/\/doi.org\/10.1155\/2013\/893638","relation":{},"ISSN":["2090-6765","2090-6773"],"issn-type":[{"value":"2090-6765","type":"print"},{"value":"2090-6773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}