{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T18:01:13Z","timestamp":1772560873678,"version":"3.50.1"},"reference-count":15,"publisher":"Wiley","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Surgical Oncology"],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:p><jats:italic>Introduction<\/jats:italic>. Sentinel lymph node (SLN) biopsy is a vital component of staging and management of multiple cancers. The current gold standard utilizes technetium 99 (tech99) and a blue dye to detect regional nodes. While the success rate is typically over 90%, these two methods can be inconclusive or inconvenient for both patient and surgeon. We evaluated a new technique using laser-assisted ICG dye lymphangiography to identify SLN.<jats:italic>Methods<\/jats:italic>. In this retrospective analysis, we identified patients with melanoma who were candidates for SLN biopsy. In addition to tech99 and methylene blue, patients received a dermal injection of indocyanine green (ICG). The infrared signal was detected with the SPY machine (Novadaq), and nodes positive by any method were excised.<jats:italic>Results<\/jats:italic>. A total of 15 patients were evaluated, with 40 SLNs removed. Four patients were found to have nodal metastases on final pathology. 100% of these 4 nodes were identified by ICG, while only 75% (3\/4) were positive for tech99 and\/or methylene blue. Furthermore, none of the nodes missed by ICG (4\/40) had malignant cells.<jats:italic>Conclusion<\/jats:italic>. ICG dye lymphangiography is a reasonable alternative for locating SLNs in patients with melanoma. Prospective studies are needed to better ascertain the full functionality of this technique.<\/jats:p>","DOI":"10.1155\/2013\/904214","type":"journal-article","created":{"date-parts":[[2013,12,8]],"date-time":"2013-12-08T16:02:03Z","timestamp":1386518523000},"page":"1-4","source":"Crossref","is-referenced-by-count":4,"title":["Sentinel Lymph Node Detection Using Laser-Assisted Indocyanine Green Dye Lymphangiography in Patients with Melanoma"],"prefix":"10.1155","volume":"2013","author":[{"given":"Vikalp","family":"Jain","sequence":"first","affiliation":[{"name":"Department of Surgery, Stony Brook University Medical Center, Stony Brook, NY 11794-8191, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brett T.","family":"Phillips","sequence":"additional","affiliation":[{"name":"Department of Surgery, Stony Brook University Medical Center, Stony Brook, NY 11794-8191, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9392-5509","authenticated-orcid":true,"given":"Nicole","family":"Conkling","sequence":"additional","affiliation":[{"name":"Stony Brook School of Medicine, Stony Brook University Medical Center, Stony Brook, NY 11794, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4822-4612","authenticated-orcid":true,"given":"Colette","family":"Pameijer","sequence":"additional","affiliation":[{"name":"Department of Surgery, Stony Brook University Medical Center, Stony Brook, NY 11794-8191, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(98)70121-7"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2007.02.032"},{"issue":"13","key":"2","doi-asserted-by":"crossref","first-page":"4112","DOI":"10.1245\/s10434-012-2478-0","volume":"19","year":"2012","journal-title":"Annals of Surgical Oncology"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2004.12.009"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-009-0858-x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-010-0760-z"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2007.12.074"},{"issue":"12","key":"8","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1093\/jjco\/29.12.604","volume":"29","year":"1999","journal-title":"Japanese Journal of Clinical Oncology"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2011.01340.x"},{"issue":"6","key":"11","doi-asserted-by":"crossref","first-page":"1988","DOI":"10.1245\/s10434-011-2180-7","volume":"19","year":"2012","journal-title":"Annals of Surgical Oncology"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1002\/jso.23045"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2010.1237"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10634.x"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-009-0594-2"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.33.1884"}],"container-title":["International Journal of Surgical Oncology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijso\/2013\/904214.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijso\/2013\/904214.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijso\/2013\/904214.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T23:53:30Z","timestamp":1498089210000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/ijso\/2013\/904214\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":15,"alternative-id":["904214","904214"],"URL":"https:\/\/doi.org\/10.1155\/2013\/904214","relation":{},"ISSN":["2090-1402","2090-1410"],"issn-type":[{"value":"2090-1402","type":"print"},{"value":"2090-1410","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013]]}}}