{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T01:35:48Z","timestamp":1791250548012,"version":"4.1.0"},"reference-count":55,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"vor","delay-in-days":273,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"},{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"crossref","award":["CZ.1.05\/1.1.00\/02.0068"],"award-info":[{"award-number":["CZ.1.05\/1.1.00\/02.0068"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"crossref","award":["NT\/13437"],"award-info":[{"award-number":["NT\/13437"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003243","name":"Ministerstvo Zdravotnictv\u00ed Cesk\u00e9 Republiky","doi-asserted-by":"publisher","award":["CZ.1.05\/1.1.00\/02.0068"],"award-info":[{"award-number":["CZ.1.05\/1.1.00\/02.0068"]}],"id":[{"id":"10.13039\/501100003243","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003243","name":"Ministerstvo Zdravotnictv\u00ed Cesk\u00e9 Republiky","doi-asserted-by":"publisher","award":["NT\/13437"],"award-info":[{"award-number":["NT\/13437"]}],"id":[{"id":"10.13039\/501100003243","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Maimonides Medical Foundation","award":["CZ.1.05\/1.1.00\/02.0068"],"award-info":[{"award-number":["CZ.1.05\/1.1.00\/02.0068"]}]},{"name":"Maimonides Medical Foundation","award":["NT\/13437"],"award-info":[{"award-number":["NT\/13437"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Neural Plasticity"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:p>Traditionally, the pathophysiology of cervical dystonia has been regarded mainly in relation to neurochemical abnormities in the basal ganglia. Recently, however, substantial evidence has emerged for cerebellar involvement. While the absence of neurological \u201ccerebellar signs\u201d in most dystonia patients may be considered at least provoking, there are more subtle indications of cerebellar dysfunction in complex, demanding tasks. Specifically, given the role of the cerebellum in the neural representation of time, in the millisecond range, dysfunction to this structure is considered to be of greater importance than dysfunction of the basal ganglia. In the current study, we investigated the performance of cervical dystonia patients on a computer task known to engage the cerebellum, namely, the interception of a moving target with changing parameters (speed, acceleration, and angle) with a simple response (pushing a button). The cervical dystonia patients achieved significantly worse results than a sample of healthy controls. Our results suggest that the cervical dystonia patients are impaired at integrating incoming visual information with motor responses during the prediction of upcoming actions, an impairment we interpret as evidence of cerebellar dysfunction.<\/jats:p>","DOI":"10.1155\/2013\/908741","type":"journal-article","created":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T17:01:56Z","timestamp":1380646916000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["The Mechanisms of Movement Control and Time Estimation in Cervical Dystonia Patients"],"prefix":"10.1155","volume":"2013","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5656-5164","authenticated-orcid":false,"given":"Pavel","family":"Filip","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ovidiu V.","family":"Lungu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel J.","family":"Shaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Kasparek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Bare\u0161","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,10]]},"reference":[{"key":"e_1_2_7_1_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.50.5_Suppl_5.S1"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25475"},{"key":"e_1_2_7_3_2","first-page":"1090","article-title":"Uber eine eigenartige kramotkrankheit des kindlichen und jugendlichen alters (dysbasia lordotica progressiva, dystonia musculorum deformans)","volume":"30","author":"Oppenheim H.","year":"1911","journal-title":"Neurologie Centralblatt"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10142"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.64.1.20"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870030410"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0b013e32832d9ef3"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2011.04.027"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2013.01.003"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000143152.45801.ca"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23321"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000094240.93745.83"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-010-5468-9"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00029330-200608010-00006"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00041327-200303000-00003"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2010.10.010"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2012.05.007"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10301"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2010.02.016"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaac.2011.02.014"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2009.06.009"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2010.12.009"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-007-0857-8"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12311-010-0237-y"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12311-009-0133-5"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1552-6569.2011.00663.x"},{"key":"e_1_2_7_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh065"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2010.113"},{"key":"e_1_2_7_29_2","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhp194"},{"key":"e_1_2_7_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-006-0791-1"},{"key":"e_1_2_7_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2008.09.007"},{"key":"e_1_2_7_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-4388(03)00036-9"},{"key":"e_1_2_7_33_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21603"},{"key":"e_1_2_7_34_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awq012"},{"key":"e_1_2_7_35_2","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.134.4.382"},{"key":"e_1_2_7_36_2","article-title":"Clinical assessments of patients with cervical dystonia","volume":"25","author":"Consky E. S.","year":"1994","journal-title":"Neurological Disease and Therapy"},{"key":"e_1_2_7_37_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/115.5.1323"},{"key":"e_1_2_7_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.baga.2012.05.003"},{"key":"e_1_2_7_39_2","doi-asserted-by":"publisher","DOI":"10.1602\/neurorx.2.3.504"},{"key":"e_1_2_7_40_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20364"},{"key":"e_1_2_7_41_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awm243"},{"key":"e_1_2_7_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2011.03.040"},{"key":"e_1_2_7_43_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-007-0453-8"},{"key":"e_1_2_7_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2007.03.009"},{"key":"e_1_2_7_45_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-012-3142-4"},{"key":"e_1_2_7_46_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1002814"},{"key":"e_1_2_7_47_2","doi-asserted-by":"publisher","DOI":"10.1080\/14734220601003955"},{"key":"e_1_2_7_48_2","doi-asserted-by":"publisher","DOI":"10.1080\/14734220601142886"},{"key":"e_1_2_7_49_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410440304"},{"key":"e_1_2_7_50_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-003-0942-2"},{"key":"e_1_2_7_51_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9568.2002.02212.x"},{"key":"e_1_2_7_52_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-211-45295-0_72"},{"key":"e_1_2_7_53_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh315"},{"key":"e_1_2_7_54_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awn168"},{"key":"e_1_2_7_55_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2011.01.026"}],"container-title":["Neural Plasticity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2013\/908741","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1155\/2013\/908741","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2013\/908741","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T15:38:52Z","timestamp":1769096332000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2013\/908741"}},"subtitle":[],"editor":[{"given":"Mario U.","family":"Manto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":55,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["10.1155\/2013\/908741"],"URL":"https:\/\/doi.org\/10.1155\/2013\/908741","archive":["Portico"],"relation":{},"ISSN":["2090-5904","1687-5443"],"issn-type":[{"value":"2090-5904","type":"print"},{"value":"1687-5443","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,1]]},"assertion":[{"value":"2013-06-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-08-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-10-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"908741"}}