{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T19:20:51Z","timestamp":1769023251452,"version":"3.49.0"},"reference-count":18,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2013,2,3]],"date-time":"2013-02-03T00:00:00Z","timestamp":1359849600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"National Autonomous University of Mexico","award":["IN219413-3"],"award-info":[{"award-number":["IN219413-3"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ISRN Microbiology"],"published-print":{"date-parts":[[2013,2,3]]},"abstract":"<jats:p><jats:italic>Staphylococcus epidermidis<\/jats:italic> strains isolated from nosocomial infections represent a serious problem worldwide. In various Mexican states several reports have shown isolates from hospitals with antibiotic resistance to methicillin. In Mexico City, there is scarce information on staphylococcal infections in hospitals. Here, our research findings are shown in a four-year period study (2006\u20132010) for <jats:italic>Staphylococcus epidermidis<\/jats:italic> strains. Susceptibility and\/or resistance to antibiotics in SE strains were assessed by phenotypic and molecular methods as <jats:italic>mecA<\/jats:italic> gene by PCR, as well as the correlation with biofilm production for these isolates and the relationship to the infection site. Out of a total of 161 (66%) negative biofilm SE strains, just 103 (64%) SE strains were confirmed as MRSE by PCR to <jats:italic>mecA<\/jats:italic> gene. From 84 (34%) positive biofilm SE strains, 76 (91%) were confirmed as MRSE by PCR to <jats:italic>mecA<\/jats:italic> gene. Higher percentages of resistance to antibiotics and higher number of resistance markers were found in biofilm-forming clinical strains (9 to 14) than non-biofilm-forming SE strains (3 to 8). These research findings represent a guide to establish infection control programs for this hospital.<\/jats:p>","DOI":"10.1155\/2013\/918921","type":"journal-article","created":{"date-parts":[[2013,2,4]],"date-time":"2013-02-04T21:04:27Z","timestamp":1360011867000},"page":"1-5","source":"Crossref","is-referenced-by-count":13,"title":["Antibiotic Resistance and Biofilm Production in <i>Staphylococcus epidermidis<\/i> Strains, Isolated from a Tertiary Care Hospital in Mexico City"],"prefix":"10.1155","volume":"2013","author":[{"given":"Roberto","family":"Cabrera-Contreras","sequence":"first","affiliation":[{"name":"Department of Public Health, Faculty of Medicine, National Autonomous University of  Mexico, 04510 Mexico City, DF, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rub\u00e9n","family":"Morelos-Ram\u00edrez","sequence":"additional","affiliation":[{"name":"Department of Public Health, Faculty of Medicine, National Autonomous University of  Mexico, 04510 Mexico City, DF, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ada Nelly","family":"Galicia-Camacho","sequence":"additional","affiliation":[{"name":"Department of Public Health, Faculty of Medicine, National Autonomous University of  Mexico, 04510 Mexico City, DF, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrique","family":"Mel\u00e9ndez-Herrada","sequence":"additional","affiliation":[{"name":"Department of Microbiology and Parasitology, Faculty of Medicine, National Autonomous University of Mexico, 04510 Mexico City, DF, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"issue":"2","key":"1","first-page":"70","volume":"74","year":"2007","journal-title":"Revista Mexicana de Pediatr\u00eda"},{"key":"2","first-page":"109","volume-title":"Coagulase-negative staphylococci","year":"2006"},{"issue":"2","key":"3","first-page":"56","volume":"68","year":"2001","journal-title":"Revista Mexicana de 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