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The infection is caused by three closely related nematode parasites, namely,<jats:italic>Wuchereria bancrofti<\/jats:italic>,<jats:italic>Brugia malayi<\/jats:italic>, and<jats:italic>B. timori<\/jats:italic>, which are transmitted to human through mosquitoes of<jats:italic>Anopheles<\/jats:italic>,<jats:italic>Culex<\/jats:italic>, and<jats:italic>Aedes<\/jats:italic>genera. The species have many ecological variants and are diversified in terms of their genetic fingerprint. The rapid spread of the disease and the genetic diversification cause the lymphatic filarial parasites to respond differently to diagnostic and therapeutic interventions. This in turn prompts the current challenge encountered in its management. Furthermore, most of the chemical medications used are characterized by adverse side effects. These complications urgently warrant intense prospecting on bio-chemicals that have potent efficacy against either the filarial worms or thier vector. In lieu of this, we presented a review on recent literature that reported the efficacy of filaricidal biochemicals and those employed as vector control agents. In addition, methods used for biochemical extraction, screening procedures, and structure of the bioactive compounds were also presented.<\/jats:p>","DOI":"10.1155\/2013\/986573","type":"journal-article","created":{"date-parts":[[2013,11,5]],"date-time":"2013-11-05T16:36:07Z","timestamp":1383669367000},"page":"1-13","source":"Crossref","is-referenced-by-count":10,"title":["Recent Advances on the Use of Biochemical Extracts as Filaricidal Agents"],"prefix":"10.1155","volume":"2013","author":[{"given":"Nazeh M.","family":"Al-Abd","sequence":"first","affiliation":[{"name":"Department of Parasitology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zurainee Mohamed","family":"Nor","sequence":"additional","affiliation":[{"name":"Department of Parasitology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulelah 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