{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T23:56:57Z","timestamp":1790294217633,"version":"4.1.0"},"reference-count":10,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Neurological Medicine"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Spontaneous intracerebral hemorrhage (ICH) is common and causes significant mortality and morbidity. To date, optimal medical and surgical intervention remains uncertain. A lack of definitive benefit for operative management may be attributable to adverse surgical effect, collateral tissue injury. This is particularly relevant for ICH in dominant, eloquent cortex. Minimally invasive surgery (MIS) offers the potential advantage of reduced collateral damage. MIS utilizing a parafascicular approach has demonstrated such benefit for intracranial tumor resection.<jats:italic>Methods<\/jats:italic>. We present a case of dominant hemisphere spontaneous ICH evacuated via the minimally invasive subcortical parafascicular transsulcal access clot evacuation (Mi SPACE) model. We use this report to introduce Mi SPACE and to examine the application of this novel MIS paradigm.<jats:italic>Case Presentation<\/jats:italic>. The featured patient presented with a left temporal ICH and severe global aphasia. The hematoma was evacuated via the Mi SPACE approach. Postoperative reassessments showed significant improvement. At two months, bedside language testing was normal. MRI tractography confirmed limited collateral injury.<jats:italic>Conclusions<\/jats:italic>. This case illustrates successful application of the Mi SPACE model to ICH in dominant, eloquent cortex and subcortical regions. MRI tractography illustrates collateral tissue preservation. Safety and feasibility studies are required to further assess this promising new therapeutic paradigm.<\/jats:p>","DOI":"10.1155\/2014\/102307","type":"journal-article","created":{"date-parts":[[2014,8,6]],"date-time":"2014-08-06T17:01:07Z","timestamp":1407344467000},"page":"1-4","source":"Crossref","is-referenced-by-count":6,"title":["Minimally Invasive Subcortical Parafascicular Transsulcal Access for Clot Evacuation (Mi SPACE) for Intracerebral Hemorrhage"],"prefix":"10.1155","volume":"2014","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3472-0271","authenticated-orcid":true,"given":"Benjamin","family":"Ritsma","sequence":"first","affiliation":[{"name":"Division of Physical Medicine & Rehabilitation, University of Ottawa, The Ottawa Hospital, Ottawa, ON, Canada K1H 8M2"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3134-1249","authenticated-orcid":true,"given":"Amin","family":"Kassam","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, University of Ottawa, The Ottawa Hospital, Ottawa, ON, Canada K1H 8L6"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dariush","family":"Dowlatshahi","sequence":"additional","affiliation":[{"name":"Division of Neurology, University of Ottawa, The Ottawa Hospital, Civic Campus, 1053 Carling Avenue, Room C2184, Ottawa, ON, Canada K1Y 4E9"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thanh","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Division of Neuroradiology, University of Ottawa, The Ottawa Hospital, Ottawa, ON, Canada K1H 8L6"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8226-4883","authenticated-orcid":true,"given":"Grant","family":"Stotts","sequence":"additional","affiliation":[{"name":"Division of Neurology, University of Ottawa, The Ottawa Hospital, Civic Campus, 1053 Carling Avenue, Room C2184, Ottawa, ON, Canada K1Y 4E9"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2010.146"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1097\/MCC.0b013e328342f823"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0b013e3181ec611b"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.640284"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(12)70104-7"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2012.02.022"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1186\/1745-6215-12-124"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1080\/02688699943501"},{"key":"9","volume":"2","year":"2007"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.56.10.1294"}],"container-title":["Case Reports in Neurological Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crinm\/2014\/102307.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crinm\/2014\/102307.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crinm\/2014\/102307.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,18]],"date-time":"2016-08-18T07:37:49Z","timestamp":1471505869000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crinm\/2014\/102307\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":10,"alternative-id":["102307","102307"],"URL":"https:\/\/doi.org\/10.1155\/2014\/102307","relation":{},"ISSN":["2090-6668","2090-6676"],"issn-type":[{"value":"2090-6668","type":"print"},{"value":"2090-6676","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}