{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T21:32:13Z","timestamp":1779053533903,"version":"3.51.4"},"reference-count":26,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["0316166B"],"award-info":[{"award-number":["0316166B"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Hematology"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>The WHO classification of lymphomas allows for a group of diseases that have features intermediate between those of Burkitt lymphoma and diffuse large B-cell lymphoma. These are a diverse group of diseases whose genetics and clinical course are yet to be fully described. We report an unusual case of high grade B-cell lymphoma, intermediate between DLBCL and BL, lacking CD10 expression in which the chromosomal translocation t(3;8)(q27;q24) was found to be the sole chromosomal abnormality. FISH analysis demonstrated juxtaposition of the<jats:italic>BCL6<\/jats:italic>and<jats:italic>MYC<\/jats:italic>loci without obvious involvement of the<jats:italic>IGH<\/jats:italic>locus, suggesting constitutive<jats:italic>MYC<\/jats:italic>expression due to promoter substitution. The patient responded to intensive chemotherapy and remains in remission two years after finishing therapy.<\/jats:p>","DOI":"10.1155\/2014\/120714","type":"journal-article","created":{"date-parts":[[2014,10,1]],"date-time":"2014-10-01T17:01:18Z","timestamp":1412182878000},"page":"1-5","source":"Crossref","is-referenced-by-count":4,"title":["A Double Hit CD10-Negative B-Cell Lymphoma with t(3;8)(q27;q24) Leading to Juxtaposition of the<i>BCL6<\/i>and<i>MYC<\/i>Loci Associated with Good Clinical Outcome"],"prefix":"10.1155","volume":"2014","author":[{"given":"Lucinda","family":"Sanders","sequence":"first","affiliation":[{"name":"Department of Haematology, University Hospitals of Leicester, Leicester LE1 5WW, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1870-9782","authenticated-orcid":true,"given":"Sandrine","family":"Jayne","sequence":"additional","affiliation":[{"name":"Ernest and Helen Scott Haematological Research Institute and Department of Biochemistry, University of Leicester, Leicester LE1 9HN, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ben","family":"Kennedy","sequence":"additional","affiliation":[{"name":"Department of Haematology, University Hospitals of Leicester, Leicester LE1 5WW, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fiona","family":"Miall","sequence":"additional","affiliation":[{"name":"Department of Haematology, University Hospitals of Leicester, Leicester LE1 5WW, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sietse M.","family":"Aukema","sequence":"additional","affiliation":[{"name":"Christian-Albrechts-University Kiel and Universitatsklinikum Schleswig-Holstein, Campus Kiel, Arnold Heller Stra\u00dfe 3, 24105 Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reiner","family":"Siebert","sequence":"additional","affiliation":[{"name":"Christian-Albrechts-University Kiel and Universitatsklinikum Schleswig-Holstein, Campus Kiel, Arnold Heller Stra\u00dfe 3, 24105 Kiel, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon D.","family":"Wagner","sequence":"additional","affiliation":[{"name":"Ernest and Helen Scott Haematological Research Institute and Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester LE1 9HN, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin J. 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