{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T03:36:53Z","timestamp":1774669013740,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Dermatological Medicine"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Pemphigus vulgaris is an autoimmune blistering disease affecting the mucous membrane and skin. In 50 to 70% of cases, the initial manifestations of pemphigus vulgaris are oral lesions which may be followed by skin lesions. But it is unusual for the disease to present with initial and solitary persistent lower lip lesions without progression to any other location.<jats:italic>Main Observations<\/jats:italic>. We report a 41-year-old woman with dry crusted lesions only on the lower lip, clinically resembling actinic cheilitis and erosive lichen planus, but histopathological evaluation showed unexpected results of suprabasal acantholysis and cleft compatible with pemphigus vulgaris. We treated her with intralesional triamcinolone 10\u2009mg\/mL for 2 sessions and 2\u2009g cellcept daily. Patient showed excellent response and lesions resolved completely within 2 months. In one-year follow-up, there was no evidence of relapse or any additional lesion on the other sites.<jats:italic>Conclusion<\/jats:italic>. Cheilitis may be the initial and sole manifestation of pemphigus vulgaris. Localized and solitary lesions of pemphigus vulgaris can be treated and controlled without systemic corticosteroids.<\/jats:p>","DOI":"10.1155\/2014\/147197","type":"journal-article","created":{"date-parts":[[2014,9,25]],"date-time":"2014-09-25T17:03:45Z","timestamp":1411664625000},"page":"1-3","source":"Crossref","is-referenced-by-count":3,"title":["Pemphigus Vulgaris Presented with Cheilitis"],"prefix":"10.1155","volume":"2014","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6791-0218","authenticated-orcid":true,"given":"Zaheer","family":"Abbas","sequence":"first","affiliation":[{"name":"Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Vahdate Eslami Square, Vahdate Eslami Avenue, Tehran 11996, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zahra","family":"Safaie Naraghi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Vahdate Eslami Square, Vahdate Eslami Avenue, Tehran 11996, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elham","family":"Behrangi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Rasoul-e Akram Hospital, Iran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.136.12.1569"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2008.070258"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1999.02612.x"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1177\/154411130201300504"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-3083.2002.00461.x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2004.02501.x"},{"key":"7","volume-title":"Immunobullous diseases","volume":"2","year":"2004"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.6.572"},{"issue":"6, article 7","key":"9","volume":"15","year":"2009","journal-title":"Dermatology Online Journal"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(91)90360-B"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12874456"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.127.6.843"},{"issue":"2","key":"13","first-page":"63","volume":"4","year":"1995","journal-title":"Epithelial Cell Biology"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetimm.2007.02.004"}],"container-title":["Case Reports in Dermatological Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cridm\/2014\/147197.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cridm\/2014\/147197.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cridm\/2014\/147197.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,7,28]],"date-time":"2016-07-28T08:20:15Z","timestamp":1469694015000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/cridm\/2014\/147197\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":14,"alternative-id":["147197","147197"],"URL":"https:\/\/doi.org\/10.1155\/2014\/147197","relation":{},"ISSN":["2090-6463","2090-6471"],"issn-type":[{"value":"2090-6463","type":"print"},{"value":"2090-6471","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}