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Complete blood count parameters were recorded prior to and three-months following the treatment.<jats:italic>Results<\/jats:italic>. Both platelet counts and the mean platelet volume were significantly decreased following the treatment. No significant differences were noted on the levels of hemoglobin, hematocrit, and white blood cell count.<jats:italic>Conclusion<\/jats:italic>. Platelet counts and mean platelet volume significantly decreased following isotretinoin treatment. Since the decrease of platelet counts and the mean platelet volume was seen concomitantly, it is concluded that the effect of isotretinoin was through the suppression of bone marrow.<\/jats:p>","DOI":"10.1155\/2014\/156464","type":"journal-article","created":{"date-parts":[[2014,1,29]],"date-time":"2014-01-29T21:33:53Z","timestamp":1391031233000},"page":"1-4","source":"Crossref","is-referenced-by-count":21,"title":["Effects of Isotretinoin on the Platelet Counts and the Mean Platelet Volume in Patients with Acne Vulgaris"],"prefix":"10.1155","volume":"2014","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5372-0712","authenticated-orcid":true,"given":"Arzu","family":"Ataseven","sequence":"first","affiliation":[{"name":"Department of Dermatology, Konya Training and Research Hospital, Meram, Konya 42023, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aynur","family":"Ugur Bilgin","sequence":"additional","affiliation":[{"name":"Department of Hematology, Meram 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