{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T22:37:15Z","timestamp":1767825435467,"version":"3.49.0"},"reference-count":40,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"Tehran University of Medical Sciences Research"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Pediatrics"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>.<jats:italic>H. pylori<\/jats:italic>infection leads to chronic gastritis in both children and adults. But recently, there are arising theories of its protective effect in diarrheal diseases.<jats:italic>Aim<\/jats:italic>. To explore the prevalence of<jats:italic>H. pylori<\/jats:italic>infection in children with bacterial diarrhea and compare it with healthy controls.<jats:italic>Patients and Methods<\/jats:italic>. Two matched groups consisted of 122 consecutive children, aged 24\u201372 months old, with acute bacterial diarrhea, who had Shigellosis (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>N<\/mml:mi><mml:mo>=<\/mml:mo><mml:mtext>68<\/mml:mtext><\/mml:mrow><\/mml:math>) and Salmonellosis (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>N<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>54<\/mml:mn><\/mml:mrow><\/mml:math>) as patients group and 204 healthy asymptomatic children as control group enrolled in this study.<jats:italic>Results<\/jats:italic>. The prevalence of<jats:italic>H. pylori<\/jats:italic>infection in healthy control children was significantly higher than in patients group, (odds ratio = 3.6, 95% CI: 1.33\u20139.5,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mrow><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.007<\/mml:mn><\/mml:mrow><\/mml:math>). In our study, only 2\/54<jats:italic>Salmonella<\/jats:italic>infected patients and 3\/68 of Shigellosis had evidence of<jats:italic>H. pylori<\/jats:italic>infection, while normal control children had 27\/204 infected individuals.<jats:italic>Conclusion<\/jats:italic>.<jats:italic>H. pylori<\/jats:italic>infection may play a protective role against bacterial diarrhea in children. So it is important to consider all of the positive and negative aspects of<jats:italic>H. pylori<\/jats:italic>infection before its eradication.<\/jats:p>","DOI":"10.1155\/2014\/191643","type":"journal-article","created":{"date-parts":[[2014,2,19]],"date-time":"2014-02-19T22:06:34Z","timestamp":1392847594000},"page":"1-5","source":"Crossref","is-referenced-by-count":8,"title":["The Relation between<i>Helicobacter pylori<\/i>Infection and Acute Bacterial Diarrhea in Children"],"prefix":"10.1155","volume":"2014","author":[{"given":"Maryam","family":"Monajemzadeh","sequence":"first","affiliation":[{"name":"Clinical and Surgical Pathology, Department of Pathology, Children Medical Center Hospital, Tehran University of Medical Sciences, Tehran 14161351, Iran"},{"name":"Pediatric Infectious Disease Research Center, Children Medical Center Hospital, Tehran University of Medical Sciences, Tehran 14161351, 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