{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T04:35:45Z","timestamp":1724301345653},"reference-count":30,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. We aimed to evaluate risk factors for ventilator-associated pneumonia (VAP) due to<jats:italic>Acinetobacter baumannii<\/jats:italic>(AbVAP) in critically ill patients.<jats:italic>Methods<\/jats:italic>. This was a prospective observational study conducted in an intensive care unit (ICU) of a district hospital (6 beds). Consecutive patients were eligible for enrolment if they required mechanical ventilation for<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mo>&gt;<\/mml:mo><\/mml:mrow><\/mml:math>48 hours and hospitalization for<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mo>&gt;<\/mml:mo><\/mml:mrow><\/mml:math>72 hours. Clinical, microbiological, and laboratory parameters were assessed as risk factors for AbVAP by univariate and multivariate analysis.<jats:italic>Results<\/jats:italic>. 193 patients were included in the study. Overall, VAP incidence was 23.8% and AbVAP, 11.4%. Previous hospitalization of another patient with<jats:italic>Acinetobacter baumannii<\/jats:italic>infection was the only independent risk factor for AbVAP (OR (95% CI) 12.016 (2.282\u201319.521)<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:math>). ICU stay<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mo stretchy=\"false\">(<\/mml:mo><mml:mn>25<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>17<\/mml:mn><\/mml:math>versus<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mn>12<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>9<\/mml:mn><mml:mi>\u00a0<\/mml:mi><mml:mi>\u2009<\/mml:mi><mml:mi>\u2009<\/mml:mi><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><mml:mo stretchy=\"false\">)<\/mml:mo><\/mml:math>, the incidence of other infections (OR (95% CI) 9.485 (1.640\u201310.466)<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.002<\/mml:mn><mml:mo stretchy=\"false\">)<\/mml:mo><\/mml:math>(urinary tract infection, catheter related infection, and bacteremia), or sepsis (OR (95% CI) 10.400 (3.749\u201310.466)<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><mml:mo stretchy=\"false\">)<\/mml:mo><\/mml:math>were significantly increased in patients with AbVAP compared to patients without VAP; no difference was found with respect to ICU mortality.<jats:italic>Conclusion<\/jats:italic>. ICU admission or the hospitalization of patients infected by<jats:italic>Acinetobacter baumannii<\/jats:italic>increases the risk of AbVAP by subsequent patients.<\/jats:p>","DOI":"10.1155\/2014\/193516","type":"journal-article","created":{"date-parts":[[2014,7,2]],"date-time":"2014-07-02T21:07:50Z","timestamp":1404335270000},"page":"1-7","source":"Crossref","is-referenced-by-count":15,"title":["<i>Acinetobacter baumannii<\/i>Infection in Prior ICU Bed Occupants Is an Independent Risk Factor for Subsequent Cases of Ventilator-Associated Pneumonia"],"prefix":"10.1155","volume":"2014","author":[{"given":"Eirini","family":"Tsakiridou","sequence":"first","affiliation":[{"name":"Department of Critical Care Medicine, University Hospital of Larisa and School of Medicine, University of Thessaly, Biopolis, 41000 Larisa, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Demosthenes","family":"Makris","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, University Hospital of Larisa and School of Medicine, University of Thessaly, Biopolis, 41000 Larisa, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zoe","family":"Daniil","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, University Hospital of Larisa and School of Medicine, University of Thessaly, Biopolis, 41000 Larisa, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Efstratios","family":"Manoulakas","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, University Hospital of Larisa and School of Medicine, University of Thessaly, Biopolis, 41000 Larisa, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasiliki","family":"Chatzipantazi","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, General Hospital of Serres, 62100 Serres, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Odysseas","family":"Vlachos","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, General Hospital of Serres, 62100 Serres, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grigorios","family":"Xidopoulos","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, General Hospital of Serres, 62100 Serres, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olympia","family":"Charalampidou","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, General Hospital of Serres, 62100 Serres, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Epaminondas","family":"Zakynthinos","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, University Hospital of Larisa and School of Medicine, University of Thessaly, Biopolis, 41000 Larisa, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.165.7.2105078"},{"issue":"6","key":"2","first-page":"742","volume":"50","year":"2005","journal-title":"Respiratory Care"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1378\/chest.130.1.251"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-37918"},{"issue":"7","key":"5","first-page":"617","volume":"25","year":"2004","journal-title":"Zhonghua Liu Xing Bing Xue Za Zhi"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1378\/chest.112.4.1050"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00156906"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-005-2598-0"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir323"},{"issue":"1","key":"10","first-page":"126","volume":"8","year":"2014","journal-title":"Health Science Journal"},{"issue":"4","key":"11","first-page":"261","volume":"68","year":"2002","journal-title":"Minerva Anestesiologica"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200405-644ST"},{"issue":"6","key":"13","first-page":"714","volume":"50","year":"2005","journal-title":"Respiratory Care"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2008.03.002"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-003-1662-x"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2010.03420.x"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-6553(81)80091-0"},{"issue":"13","key":"18","first-page":"1834","volume":"16","year":"2012","journal-title":"European review for medical and pharmacological sciences"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1086\/529198"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.162.3.9905050"},{"issue":"9","key":"21","doi-asserted-by":"crossref","first-page":"2962","DOI":"10.1128\/JCM.37.9.2962-2967.1999","volume":"37","year":"1999","journal-title":"Journal of Clinical Microbiology"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/14.1.83"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-012-2808-5"},{"issue":"10","key":"25","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1111\/j.1469-0691.2012.03956.x","volume":"18","year":"2012","journal-title":"Clinical Microbiology and Infection"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00058-07"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1016\/j.resmic.2005.09.011"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1186\/cc4869"},{"issue":"3","key":"29","first-page":"15","volume":"30","year":"2012","journal-title":"Translational Medicine @ UniSa"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/850547"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1378\/chest.101.1.194"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2014\/193516.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2014\/193516.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2014\/193516.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,21]],"date-time":"2020-08-21T22:46:23Z","timestamp":1598049983000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/bmri\/2014\/193516\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":30,"alternative-id":["193516","193516"],"URL":"https:\/\/doi.org\/10.1155\/2014\/193516","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}