{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T17:44:22Z","timestamp":1778435062414,"version":"3.51.4"},"reference-count":27,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gastroenterology Research and Practice"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>The aim of this study was to investigate the diagnostic usefulness of real-time elastography (RTE) for liver fibrosis in chronic viral hepatitis B (CHB) and C (CHC). Fifty-one and thirty-two of the patients were diagnosed with CHB and CHC, respectively. Enrolled patients underwent liver biopsy and RTE. The FIB-4 index and aspartate transaminase-to-platelet ratio index (APRI) were also measured. The liver fibrosis index (LFI) by RTE increased significantly with the Knodell fibrosis stage:<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mn>3.14<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>0.62<\/mml:mn><\/mml:math>for F0,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mn>3.28\u2009<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>\u20090.42<\/mml:mn><\/mml:math>for F1,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mn>3.43\u2009<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>\u20090.53<\/mml:mn><\/mml:math>for F3, and<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mn>4.09\u2009<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>\u20091.03<\/mml:mn><\/mml:math>for F4 (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.000<\/mml:mn><\/mml:math>). LFI as well as APRI, FIB-4, platelet, albumin, and prothrombin time showed the difference in patients with advanced fibrosis (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mrow><mml:mo>\u2265<\/mml:mo><\/mml:mrow><\/mml:math>F3) and those with mild fibrosis (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mrow><mml:mo>\u2264<\/mml:mo><\/mml:mrow><\/mml:math>F1). In addition, RTE had better discrimination power between<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\"><mml:mrow><mml:mo>\u2265<\/mml:mo><\/mml:mrow><\/mml:math>F3 and F4 than between FIB-4 and APRI. In CHC patients, the area under receiver operating characteristic curves of RTE for advanced fibrosis was higher than that in CHB patients (0.795 versus 0.641). RTE is useful for the assessment of advanced fibrosis in patients with CHB and CHC and has better discrimination power than other serologic markers.<\/jats:p>","DOI":"10.1155\/2014\/210407","type":"journal-article","created":{"date-parts":[[2014,8,10]],"date-time":"2014-08-10T21:02:39Z","timestamp":1407704559000},"page":"1-7","source":"Crossref","is-referenced-by-count":5,"title":["Diagnostic Usefulness of Real-Time Elastography for Liver Fibrosis in Chronic Viral Hepatitis B and C"],"prefix":"10.1155","volume":"2014","author":[{"given":"Young Woon","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Incheon St. Mary\u2019s Hospital, The Catholic University of Korea, Incheon 403-720, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jung Hyun","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Incheon St. Mary\u2019s Hospital, The Catholic University of Korea, Incheon 403-720, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong Won","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Seoul St. Mary\u2019s Hospital, The Catholic University of Korea, Seoul 403-720, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min Ju","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Incheon St. Mary\u2019s Hospital, The Catholic University of Korea, Incheon 403-720, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Byong Sun","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Incheon St. Mary\u2019s Hospital, The Catholic University of Korea, Incheon 403-720, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyu Won","family":"Chung","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Incheon St. Mary\u2019s Hospital, The Catholic University of Korea, Incheon 403-720, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eun Su","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Pathology, Incheon St. Mary\u2019s Hospital, The Catholic University of Korea, Incheon 403-720, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soon Woo","family":"Nam","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Incheon St. Mary\u2019s Hospital, The Catholic University of Korea, Incheon 403-720, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"issue":"1","key":"1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.jhep.2012.02.010","volume":"57","year":"2012","journal-title":"Journal of 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