{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T22:40:48Z","timestamp":1769640048960,"version":"3.49.0"},"reference-count":19,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Scientific World Journal"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p><jats:italic>Purpose.<\/jats:italic>To determine the differences in risk factors for retinopathy of prematurity (ROP) in paired twins.<jats:italic>Methods.<\/jats:italic>A retrospective medical record review was performed for all paired twins screened for ROP between 2007 and 2012. Screening was offered to very low birth weight (\u22641500 grams) and preterm (\u226432 weeks) neonates. Twins 1 and 2 were categorized based on the order of delivery. Maternal and neonatal covariates were analyzed using univariate and multivariate regression analyses for both ROP and Type 1 ROP.<jats:italic>Results.<\/jats:italic>In 34 pairs of Chinese twins, the mean gestational age (GA) was 30.2 \u00b1 2.0 weeks. In Twin 1, smaller GA (OR = 0.44,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.02<\/mml:mn><\/mml:math>), higher mean oxygen concentration (OR = 1.34,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.03<\/mml:mn><\/mml:math>), presence of thrombocytopenia (OR = 1429.60,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.0001<\/mml:mn><\/mml:math>), and intraventricular hemorrhage (OR = 18.67,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.03<\/mml:mn><\/mml:math>) were significant risk factors for ROP. For Twin 2, a smaller GA (OR = 0.45,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.03<\/mml:mn><\/mml:math>) was the only risk factor. There were no significant risk factors for ROP in Twin 1 or Twin 2 on multivariate analysis.<jats:italic>Conclusion.<\/jats:italic>In Chinese twin pairs, smaller GA was the only common risk factor for ROP while Twin 1 was more susceptible to the postnatal risks for ROP.<\/jats:p>","DOI":"10.1155\/2014\/212183","type":"journal-article","created":{"date-parts":[[2014,10,23]],"date-time":"2014-10-23T21:55:04Z","timestamp":1414101304000},"page":"1-7","source":"Crossref","is-referenced-by-count":7,"title":["Differences in Risk Factors for Retinopathy of Prematurity Development in Paired Twins: A Chinese Population Study"],"prefix":"10.1155","volume":"2014","author":[{"given":"Gordon S. K.","family":"Yau","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Caritas Medical Centre, 111 Wing Hong Street, Kowloon, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacky W. Y.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Caritas Medical Centre, 111 Wing Hong Street, Kowloon, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor T. Y.","family":"Tam","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Caritas Medical Centre, 111 Wing Hong Street, Kowloon, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stan","family":"Yip","sequence":"additional","affiliation":[{"name":"Department of Applied Mathematics, The Hong Kong Polytechnic University, Kowloon, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edith","family":"Cheng","sequence":"additional","affiliation":[{"name":"Centre of Health Behaviours Research, The Chinese University of Hong Kong, Kowloon, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine C. L.","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Applied Mathematics, The Hong Kong Polytechnic University, Kowloon, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin C. Y.","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Caritas Medical Centre, 111 Wing Hong Street, Kowloon, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Can Y. F.","family":"Yuen","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Caritas Medical Centre, 111 Wing Hong Street, Kowloon, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1001\/archopht.1945.00890150047006","volume":"33","year":"1945","journal-title":"Archives of Ophthalmology"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/S1091-8531(99)70091-1"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2007.126201"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2007.126508"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2008.145136"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.83.4.425"},{"issue":"5","key":"7","doi-asserted-by":"crossref","first-page":"268","DOI":"10.3928\/0191-3913-19900901-13","volume":"27","year":"1990","journal-title":"Journal of Pediatric Ophthalmology and Strabismus"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.4103\/0301-4738.62645"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2011.208"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-012-9533-5"},{"key":"11","year":"2013"},{"issue":"3","key":"12","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0378-3782(96)01747-1","volume":"46","year":"1996","journal-title":"Early Human Development"},{"issue":"12","key":"13","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1001\/archopht.121.12.1684","volume":"121","year":"2003","journal-title":"Archives of Ophthalmology"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.123.7.991"},{"key":"15","year":"2014"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1047"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1093\/biomet\/80.1.27"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(94)70336-1"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-1126"}],"container-title":["The Scientific World Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2014\/212183.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2014\/212183.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2014\/212183.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,20]],"date-time":"2022-04-20T15:18:24Z","timestamp":1650467904000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/tswj\/2014\/212183\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":19,"alternative-id":["212183","212183"],"URL":"https:\/\/doi.org\/10.1155\/2014\/212183","relation":{},"ISSN":["2356-6140","1537-744X"],"issn-type":[{"value":"2356-6140","type":"print"},{"value":"1537-744X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}