{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T16:00:00Z","timestamp":1783699200558,"version":"3.55.0"},"reference-count":43,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,6,25]],"date-time":"2014-06-25T00:00:00Z","timestamp":1403654400000},"content-version":"vor","delay-in-days":175,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"Academic Research Grant","award":["23590867"],"award-info":[{"award-number":["23590867"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:p>Poststroke patients with functional constipation, assessed by the Rome III criteria, from 6 hospitals were recruited in a study on the effects of the traditional Japanese medicine Daikenchuto (DKT) on constipation. Thirty\u2010four patients (17 men and 17 women; mean age: 78.1 \u00b1 11.6 years) were randomly assigned to 2 groups; all patients received conventional therapy for constipation, and patients in the DKT group received 15\u2009g\/day of DKT for 4 weeks. Constipation scoring system (CSS) points and the gas volume score (GVS) (the measure of the intestinal gas volume calculated from plain abdominal radiographs) were recorded before and after a 4\u2010week observation period. The total score on the CSS improved significantly in the DKT group compared to the control (<jats:italic>P<\/jats:italic> &lt; 0.01). In addition, scores for some CSS subcategories (frequency of bowel movements, feeling of incomplete evacuation, and need for enema\/disimpaction) significantly improved in the DKT group (<jats:italic>P<\/jats:italic> &lt; 0.01, <jats:italic>P<\/jats:italic> = 0.049, and <jats:italic>P<\/jats:italic> = 0.03, resp.). The GVS was also significantly reduced in the DKT group compared to the control (<jats:italic>P<\/jats:italic> = 0.03). DKT in addition to conventional therapy is effective in treating functional constipation in poststroke patients. This study was a randomized controlled trial and was registered in the UMIN Clinical Trial Registry (no. <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/upload.umin.ac.jp\/cgi-open-bin\/ctr\/ctr.cgi?function=brows&amp;action=brows&amp;type=summary&amp;recptno=R000008711&amp;language=E\">UMIN000007393<\/jats:ext-link>).<\/jats:p>","DOI":"10.1155\/2014\/231258","type":"journal-article","created":{"date-parts":[[2014,7,8]],"date-time":"2014-07-08T12:48:27Z","timestamp":1404823707000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Traditional Japanese Medicine Daikenchuto Improves Functional Constipation in Poststroke 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