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HPO, namely, \u201ccharacterization,\u201d can be understood as a sorting and generalization of the manifestations shown by people with diseases on the basis of the phenomics. Syndrome is the overall \u201cmanifestation\u201d of human body pathological and physiological changes expressed by four diagnostic methods\u2019 information. The four diagnostic methods\u2019 data could be the most objective and direct manifestations of human body under morbid conditions. In this aspect, it is consistent with the connation of \u201ccharacterization.\u201d Meanwhile, the four diagnostic methods\u2019 data also equip us with features of characterization in HPO. In our study, we compared 107 pieces of four diagnostic methods\u2019 information with the \u201ccharacterization database\u201d to further analyze data of four diagnostic methods\u2019 characterization in accordance with the common characteristics of four diagnostic methods\u2019 information and characterization and integrated 107 pieces of four diagnostic methods\u2019 data to relevant items in HPO and finished the expansion of characterization information in HPO.<\/jats:p>","DOI":"10.1155\/2014\/240284","type":"journal-article","created":{"date-parts":[[2014,12,15]],"date-time":"2014-12-15T21:00:37Z","timestamp":1418677237000},"page":"1-16","source":"Crossref","is-referenced-by-count":3,"title":["Phenomics Research on Coronary Heart Disease Based on Human Phenotype Ontology"],"prefix":"10.1155","volume":"2014","author":[{"given":"Qi","family":"Shi","sequence":"first","affiliation":[{"name":"The Key Institute of State Administration of Traditional Chinese Medicine (Pneumonopathy 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