{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:08:58Z","timestamp":1762866538836},"reference-count":21,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Pediatrics"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>Acute leukemias are the most common childhood cancer in all age groups. Acute myeloid leukemias (AML) constitute about 15\u201320% of acute leukemias. Fatigability, pallor, fever, and bleeding are the most common presenting symptoms of AML. Hepatosplenomegaly and lymphadenopathy are commonly encountered during physical examination. In rare instances eruptions due to skin involvement and localized tumor masses (myeloid sarcoma) may be found. Myeloid sarcoma is especially seen in AML-M2 subtype. By cytogenetic analysis, in AML-M2 subtype t(8;21) is often seen and it is more probable to find inversion 16 in AML-M4Eos subtype. Herein, we present a 15-year-old girl whose initial symptom was abdominal pain for three days and her pathological sign was a large abdominal mass which was verified by imaging studies and diagnosed as myeloid sarcoma by biopsy. On bone marrow examination, she had diagnosis of AML-M2 and by cytogenetic analysis inversion 16 was positive. She was treated with AML-BFM 2004 protocol and she is being followed up in remission on her ninth month of the maintenance therapy.<\/jats:p>","DOI":"10.1155\/2014\/246169","type":"journal-article","created":{"date-parts":[[2014,12,22]],"date-time":"2014-12-22T21:13:40Z","timestamp":1419282820000},"page":"1-4","source":"Crossref","is-referenced-by-count":1,"title":["A Case of Acute Myeloid Leukemia (FAB M2) with Inversion 16 Who Presented with Pelvic Myeloid Sarcoma"],"prefix":"10.1155","volume":"2014","author":[{"given":"Mustafa","family":"\u00c7akan","sequence":"first","affiliation":[{"name":"Department of Pediatric Hematology and Oncology, Faculty of Medicine, Marmara University, Mimar Sinan Caddesi No. 41, Pendik, 34899 Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Ko\u00e7","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology and Oncology, Faculty of Medicine, Marmara University, Mimar Sinan Caddesi No. 41, Pendik, 34899 Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K\u0131v\u0131lc\u0131m","family":"Cerit","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Faculty of Medicine, Marmara University, Mimar Sinan Caddesi No. 41, Pendik, 34899 Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00fcheyla","family":"Bozkurt","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Medicine, Marmara University, Mimar Sinan Caddesi No. 41, Pendik, 34899 Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rabia","family":"Ergelen","sequence":"additional","affiliation":[{"name":"Department of Radiology, Faculty of Medicine, Marmara University, Mimar Sinan Caddesi No. 41, Pendik, 34899 Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irmak","family":"Vural","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Faculty of Medicine, Marmara University, Mimar Sinan Caddesi No. 41, Pendik, 34899 Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","first-page":"591","volume-title":"Acute myelogenous leukemia","year":"2006"},{"key":"2","first-page":"499","volume-title":"Acute myeloid leukemia","year":"2006"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1159\/000205531"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1080\/10428190290012056"},{"issue":"3","key":"5","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1002\/(SICI)1096-911X(199809)31:3<144::AID-MPO3>3.0.CO;2-B","volume":"31","year":"1998","journal-title":"Medical and Pediatric Oncology"},{"issue":"7","key":"6","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1200\/JCO.1995.13.7.1800","volume":"13","year":"1995","journal-title":"Journal of Clinical Oncology"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-103-4-620"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-03-209262"},{"key":"9","first-page":"550","volume-title":"Leukemias","year":"2011"},{"issue":"5","key":"10","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1080\/08880010390203954","volume":"20","year":"2003","journal-title":"Pediatric Hematology and Oncology"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-04-347872"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28012"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.4081\/rt.2012.e36"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1080\/10428190600967196"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-10-462440"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-01-293050"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-11-254441"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2003.04349.x"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2009.01308.x"},{"issue":"8","key":"20","first-page":"593","volume":"50","year":"2012","journal-title":"Zhonghua Er Ke Za Zhi"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.20081"}],"container-title":["Case Reports in Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripe\/2014\/246169.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripe\/2014\/246169.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripe\/2014\/246169.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,23]],"date-time":"2017-06-23T02:31:18Z","timestamp":1498185078000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/cripe\/2014\/246169\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":21,"alternative-id":["246169","246169"],"URL":"https:\/\/doi.org\/10.1155\/2014\/246169","relation":{},"ISSN":["2090-6803","2090-6811"],"issn-type":[{"value":"2090-6803","type":"print"},{"value":"2090-6811","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}