{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:03:10Z","timestamp":1740164590329,"version":"3.37.3"},"reference-count":10,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Hematology"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p><jats:italic>Objective.<\/jats:italic>The aim of this paper is to report the case of a patient diagnosed with Hermansky-Pudlak syndrome, as a result of bleeding diathesis.<jats:italic>Clinical Presentation and Intervention.<\/jats:italic>A 23-year-old male presented with recurrent epistaxis and, upon physical examination, was found to be remarkable for albinism and suborbital ecchymosis. The absence of dense bodies in the platelets was demonstrated using electron microscopy. This patient was (slowly) administered one unit of a platelet suspension, and his bleeding decreased considerably.<jats:italic>Conclusion.<\/jats:italic>This case shows that Hermansky-Pudlak syndrome should be considered in the differential diagnosis of a patient presenting with bleeding diathesis, when the clinical presentation also includes oculocutaneous albinism and visual problems.<\/jats:p>","DOI":"10.1155\/2014\/249195","type":"journal-article","created":{"date-parts":[[2014,2,20]],"date-time":"2014-02-20T16:01:29Z","timestamp":1392912089000},"page":"1-3","source":"Crossref","is-referenced-by-count":0,"title":["Hermansky-Pudlak Syndrome: A Case Report"],"prefix":"10.1155","volume":"2014","author":[{"given":"Ilhami","family":"Berber","sequence":"first","affiliation":[{"name":"Department of Haematology, Faculty of Medicine, Inonu University, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet Ali","family":"Erkurt","sequence":"additional","affiliation":[{"name":"Department of Haematology, Faculty of Medicine, Inonu University, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irfan","family":"Kuku","sequence":"additional","affiliation":[{"name":"Department of Haematology, Faculty of Medicine, Inonu University, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emin","family":"Kaya","sequence":"additional","affiliation":[{"name":"Department of Haematology, Faculty of Medicine, Inonu University, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa","family":"Koroglu","sequence":"additional","affiliation":[{"name":"Department of Haematology, Faculty of Medicine, Inonu University, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7787-2232","authenticated-orcid":true,"given":"Ilknur","family":"Nizam","sequence":"additional","affiliation":[{"name":"Department of Haematology, Faculty of Medicine, Inonu University, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Gul","sequence":"additional","affiliation":[{"name":"Department of Histology and Embryology, Faculty of Medicine, Inonu University, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Recep","family":"Bentli","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Faculty of Medicine, Inonu University, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1159\/000091609"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2011.05.009"},{"issue":"178","key":"3","first-page":"219","volume":"45","year":"1976","journal-title":"Quarterly Journal of Medicine"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1136\/adc.86.4.297"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1046\/j.1538-7836.2003.00032.x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1046\/j.0007-1048.2001.03302.x"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2006.06343.x"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2012.02842.x"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1159\/000086184"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830300307"}],"container-title":["Case Reports in Hematology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2014\/249195.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2014\/249195.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2014\/249195.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,7,28]],"date-time":"2016-07-28T14:25:15Z","timestamp":1469715915000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crihem\/2014\/249195\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":10,"alternative-id":["249195","249195"],"URL":"https:\/\/doi.org\/10.1155\/2014\/249195","relation":{},"ISSN":["2090-6560","2090-6579"],"issn-type":[{"type":"print","value":"2090-6560"},{"type":"electronic","value":"2090-6579"}],"subject":[],"published":{"date-parts":[[2014]]}}}