{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:51:42Z","timestamp":1790617902108,"version":"4.1.0"},"reference-count":73,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81170862"],"award-info":[{"award-number":["81170862"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81273424"],"award-info":[{"award-number":["81273424"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81170862"],"award-info":[{"award-number":["81170862"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81273424"],"award-info":[{"award-number":["81273424"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>The application of perfluorocarbon liquids has been well acclaimed in vitreoretinal surgery. Its unique physical properties make it an ideal intraoperative tool to improve the efficiency and safety of surgical procedures in complicated cases. The main functions of perfluorocarbon liquids in vitreoretinal surgery include relocating and fixing the detached retina, displacing the subretinal and subchoroidal to fluid anteriorly, revealing proliferative vitreous retinopathy (PVR) for further maneuvers, protecting the macula from exposure to chemicals with potential toxicity, and assisting the removal of foreign body. The related clinical applications include retinal detachment with severe proliferative vitreoretinopathy, giant tear, diabetic retinopathy (DR), retinopathy of prematurity (ROP), and posterior dislocated crystalline and intraocular lenses. The application of perfluorocarbon liquids has been expended over the past fewer years. Several PFCLs related ocular inflammations have been observed in<jats:italic>in vitro<\/jats:italic>studies, animal studies, and clinical follow-up. The complete removal of PFCLs is recommended at the end of the surgery in most cases.<\/jats:p>","DOI":"10.1155\/2014\/250323","type":"journal-article","created":{"date-parts":[[2014,3,30]],"date-time":"2014-03-30T21:02:19Z","timestamp":1396213339000},"page":"1-6","source":"Crossref","is-referenced-by-count":55,"title":["Perfluorocarbon Liquid: Its Application in Vitreoretinal Surgery and Related Ocular Inflammation"],"prefix":"10.1155","volume":"2014","author":[{"given":"Qi","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Shanghai First People\u2019s Hospital Affiliated to Shanghai Jiaotong University, No. 100 Haining Road, Shanghai 200080, China"},{"name":"Shanghai Key Laboratory of Fundus Diseases, Shanghai 200080, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Shanghai First People\u2019s Hospital Affiliated to Shanghai Jiaotong University, No. 100 Haining Road, Shanghai 200080, China"},{"name":"Shanghai Key Laboratory of Fundus Diseases, Shanghai 200080, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Shanghai First People\u2019s Hospital Affiliated to Shanghai Jiaotong University, No. 100 Haining Road, Shanghai 200080, China"},{"name":"Shanghai Key Laboratory of Fundus Diseases, Shanghai 200080, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Shanghai First People\u2019s Hospital Affiliated to Shanghai Jiaotong University, No. 100 Haining Road, Shanghai 200080, China"},{"name":"Shanghai Key Laboratory of Fundus Diseases, Shanghai 200080, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xun","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Shanghai First People\u2019s Hospital Affiliated to Shanghai Jiaotong University, No. 100 Haining Road, Shanghai 200080, China"},{"name":"Shanghai Key Laboratory of Fundus Diseases, Shanghai 200080, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/00004397-199203220-00014"},{"key":"2","year":"1994"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-008-0861-0"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6257(05)80093-1"},{"key":"5","first-page":"67","volume":"7","year":"1994","journal-title":"Ophthalmology Clinics of North America"},{"issue":"5","key":"6","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/S0002-9394(14)73197-6","volume":"116","year":"1993","journal-title":"American Journal of Ophthalmology"},{"issue":"5","key":"7","first-page":"1699","volume":"29","year":"1970","journal-title":"Federation Proceedings"},{"issue":"2","key":"8","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1097\/00006982-199212020-00010","volume":"12","year":"1992","journal-title":"Retina"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.3109\/15569527.2011.560915"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2009.175216"},{"issue":"1","key":"11","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/S0002-9394(14)74166-2","volume":"103","year":"1987","journal-title":"American Journal of Ophthalmology"},{"issue":"3730","key":"12","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1126\/science.152.3730.1755","volume":"152","year":"1966","journal-title":"Science"},{"issue":"2","key":"13","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1002\/ppul.1950140208","volume":"14","year":"1992","journal-title":"Pediatric Pulmonology"},{"key":"14","volume":"22, article 233","year":"1982","journal-title":"Investigative Ophthalmology & Visual Science"},{"key":"15","volume":"25, supplement, article 258","year":"1984","journal-title":"Investigative Ophthalmology & Visual Science"},{"issue":"6","key":"16","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/0002-9394(88)90698-8","volume":"106","year":"1988","journal-title":"American Journal of Ophthalmology"},{"issue":"12","key":"17","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1136\/bjo.79.12.1106","volume":"79","year":"1995","journal-title":"British Journal of Ophthalmology"},{"issue":"2","key":"18","first-page":"66","volume":"29","year":"1994","journal-title":"Canadian Journal of Ophthalmology"},{"issue":"4","key":"19","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/S0161-6420(95)30975-X","volume":"102","year":"1995","journal-title":"Ophthalmology"},{"issue":"2","key":"20","doi-asserted-by":"crossref","first-page":"154","DOI":"10.3928\/1542-8877-19960201-14","volume":"27","year":"1996","journal-title":"Ophthalmic Surgery and Lasers"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1097\/00006982-200310000-00003"},{"issue":"3","key":"22","first-page":"S7","volume":"12","year":"1992","journal-title":"Retina"},{"issue":"5","key":"23","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1001\/archopht.1989.01070010779046","volume":"107","year":"1989","journal-title":"Archives of Ophthalmology"},{"issue":"4","key":"24","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/S0181-5512(05)81066-6","volume":"28","year":"2005","journal-title":"Journal Francais d'Ophtalmologie"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(02)01184-3"},{"issue":"7","key":"26","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/S0161-6420(97)30168-7","volume":"104","year":"1997","journal-title":"Ophthalmology"},{"issue":"3","key":"27","first-page":"211","volume":"112","year":"1999","journal-title":"Chinese Medical Journal"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6257(99)00036-3"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.87.5.563"},{"issue":"2","key":"30","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/BF00919247","volume":"18","year":"1994","journal-title":"International Ophthalmology"},{"issue":"2","key":"31","first-page":"384.e2","volume":"157","year":"2014","journal-title":"American Journal of Ophthalmology"},{"issue":"6","key":"32","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0161-6420(89)32812-0","volume":"96","year":"1989","journal-title":"Ophthalmology"},{"issue":"8","key":"33","first-page":"537","volume":"24","year":"1993","journal-title":"Ophthalmic Surgery"},{"issue":"5","key":"35","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1097\/00006982-199414050-00012","volume":"14","year":"1994","journal-title":"Retina"},{"issue":"7","key":"36","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1007\/s00417-013-2293-8","volume":"251","year":"2013","journal-title":"Graefe'S Archive for Clinical and Experimental Ophthalmology"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.3928\/15428877-20100726-01"},{"issue":"5","key":"38","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1007\/s00417-012-2170-x","volume":"251","year":"2013","journal-title":"Graefe'S Archive for Clinical and Experimental Ophthalmology"},{"issue":"1","key":"39","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3928\/1542-8877-20020101-16","volume":"33","year":"2002","journal-title":"Ophthalmic Surgery and Lasers"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-006-0316-4"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(02)02173-6"},{"issue":"1","key":"42","doi-asserted-by":"crossref","first-page":"41","DOI":"10.3341\/kjo.2000.14.1.41","volume":"14","year":"2000","journal-title":"Korean Journal of Ophthalmology"},{"issue":"10","key":"43","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1016\/S0161-6420(92)31756-7","volume":"99","year":"1992","journal-title":"Ophthalmology"},{"issue":"3","key":"44","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0002-9394(14)70274-0","volume":"121","year":"1996","journal-title":"American Journal of Ophthalmology"},{"issue":"6","key":"45","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1177\/112067210201200614","volume":"12","year":"2002","journal-title":"European Journal of Ophthalmology"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e318196fca1"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1027764"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-006-0414-3"},{"issue":"4","key":"49","first-page":"367","volume":"11","year":"1991","journal-title":"Retina"},{"key":"50","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(00)00481-4"},{"issue":"3","key":"51","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1097\/00006982-200106000-00009","volume":"21","year":"2001","journal-title":"Retina"},{"issue":"4","key":"52","first-page":"638","volume":"31","year":"1990","journal-title":"Investigative Ophthalmology and Visual Science"},{"key":"53","doi-asserted-by":"publisher","DOI":"10.1023\/A:1006444615412"},{"key":"61","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-008-0768-9"},{"issue":"1","key":"54","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/BF00177782","volume":"233","year":"1995","journal-title":"Graefe's Archive for Clinical and Experimental Ophthalmology"},{"key":"55","doi-asserted-by":"publisher","DOI":"10.1097\/00006982-200402000-00031"},{"key":"56","doi-asserted-by":"publisher","DOI":"10.1097\/00006982-200410000-00010"},{"key":"57","doi-asserted-by":"publisher","DOI":"10.1097\/01.iae.0000244258.68148.4c"},{"key":"58","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-007-0535-3"},{"key":"59","doi-asserted-by":"publisher","DOI":"10.1007\/BF00918847"},{"issue":"7","key":"60","doi-asserted-by":"crossref","first-page":"563","DOI":"10.3109\/02713683.2012.669511","volume":"37","year":"2012","journal-title":"Current Eye Research"},{"key":"62","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e31804b3cf9"},{"key":"63","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2003.08.033"},{"key":"64","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-004-1063-z"},{"key":"65","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2005.07.028"},{"key":"66","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e3181619bd5"},{"key":"67","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e3182475b16"},{"issue":"9","key":"68","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1007\/s004170100330","volume":"239","year":"2001","journal-title":"Graefe's Archive for Clinical and Experimental Ophthalmology"},{"key":"69","doi-asserted-by":"publisher","DOI":"10.1080\/02713680590959439"},{"key":"70","doi-asserted-by":"publisher","DOI":"10.1097\/00006982-200501000-00016"},{"key":"71","doi-asserted-by":"publisher","DOI":"10.1097\/00006982-200408000-00010"},{"key":"72","doi-asserted-by":"publisher","DOI":"10.1159\/000298749"},{"key":"73","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2008.144"},{"key":"74","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2004.055178"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2014\/250323.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2014\/250323.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2014\/250323.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T10:26:18Z","timestamp":1648722378000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/bmri\/2014\/250323\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":73,"alternative-id":["250323","250323"],"URL":"https:\/\/doi.org\/10.1155\/2014\/250323","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}