{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T01:30:43Z","timestamp":1773279043179,"version":"3.50.1"},"reference-count":44,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["13\/05560-4"],"award-info":[{"award-number":["13\/05560-4"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>Methylmercury, organic form of mercury, can increase the number of abnormal sperm and decrease sperm concentration and testosterone levels possibly due to the damage caused by reactive species to germ and Leydig cells. Man\u00e1-cubiu (<jats:italic>Solanum sessiliflorum<\/jats:italic>Dunal) is a native fruit from Amazon rich in iron, zinc, niacin, pectin, and citric acid, used in foods, beverages, and medicinal purposes, since it has been useful for treatment of various diseases caused by oxidative stress or nutritional deficiency. Therefore, this study evaluated the phytoremediation potential of this fruit on damages caused by exposure to MeHg on sperm quantity and quality and the histological aspect of the testis and epididymis. Wistar male rats (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>20<\/mml:mn><\/mml:math>) were randomly allocated into four groups: Control group (received distilled water), MeHg group (140\u2009<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>\u03bc<\/mml:mi><\/mml:mrow><\/mml:math>g\/Kg),<jats:italic>Solanum<\/jats:italic>group (1% of fruit Man\u00e1-cubiu on chow), and<jats:italic>Solanum<\/jats:italic>plus MeHg group (same treatment as MeHg and Solanum group). The organs were weighted, histopathology; sperm morphology and counts were obtained. The results showed reduction in body weight gain, testis weights, reduced sperm production, and increased histopathological abnormalities in the MeHg-treated group. However, treatment with<jats:italic>Solanum<\/jats:italic>plus MeHg revealed a protective effect of this fruit on damages caused by MeHg.<\/jats:p>","DOI":"10.1155\/2014\/309631","type":"journal-article","created":{"date-parts":[[2014,3,20]],"date-time":"2014-03-20T03:01:40Z","timestamp":1395284500000},"page":"1-9","source":"Crossref","is-referenced-by-count":10,"title":["Phytoremediation Potential of Man\u00e1-Cubiu (<i>Solanum sessiliflorum<\/i>Dunal) for the Deleterious Effects of Methylmercury on the Reproductive System of Rats"],"prefix":"10.1155","volume":"2014","author":[{"given":"Raquel","family":"Frenedoso da Silva","sequence":"first","affiliation":[{"name":"Department of Morphology, Institute of Biosciences, Univ Estadual Paulista-UNESP, Distrito de Rubi\u00e3o Junior s\/n\u00ba, 18618-970 Botucatu, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela","family":"Missassi","sequence":"additional","affiliation":[{"name":"Department of Morphology, Institute of Biosciences, Univ Estadual Paulista-UNESP, Distrito de Rubi\u00e3o Junior s\/n\u00ba, 18618-970 Botucatu, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cibele","family":"dos Santos Borges","sequence":"additional","affiliation":[{"name":"Department of Morphology, Institute of Biosciences, Univ Estadual Paulista-UNESP, Distrito de Rubi\u00e3o Junior s\/n\u00ba, 18618-970 Botucatu, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elo\u00edsa","family":"Silva de Paula","sequence":"additional","affiliation":[{"name":"Department of Clinical Analyses, Toxicology and Food Sciences, School of Pharmaceutical Sciences of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, Avenida do Caf\u00e9 s\/n\u00ba, 14040-903 Ribeir\u00e3o Preto, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Fernanda","family":"Hornos Carneiro","sequence":"additional","affiliation":[{"name":"Department of Clinical Analyses, Toxicology and Food Sciences, School of Pharmaceutical Sciences of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, Avenida do Caf\u00e9 s\/n\u00ba, 14040-903 Ribeir\u00e3o Preto, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8782-0436","authenticated-orcid":true,"given":"Denise","family":"Grotto","sequence":"additional","affiliation":[{"name":"Department of Clinical Analyses, Toxicology and Food Sciences, School of Pharmaceutical Sciences of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, Avenida do Caf\u00e9 s\/n\u00ba, 14040-903 Ribeir\u00e3o Preto, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Barbosa Junior","sequence":"additional","affiliation":[{"name":"Department of Clinical Analyses, Toxicology and Food Sciences, School of Pharmaceutical Sciences of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, Avenida do Caf\u00e9 s\/n\u00ba, 14040-903 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