{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:44:46Z","timestamp":1761561886051,"version":"3.37.3"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,7,9]],"date-time":"2014-07-09T00:00:00Z","timestamp":1404864000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostic and Therapeutic Endoscopy"],"published-print":{"date-parts":[[2014,7,9]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Abnormal liver enzymes postorthotopic liver transplant (OLT) may indicate significant biliary pathology or organ rejection. There is very little known in the literature regarding the current role of diagnostic ERCP in this scenario. <jats:italic>Aim<\/jats:italic>. To review the utility of diagnostic ERCP in patients presenting with abnormal liver function tests in the setting of OLT. <jats:italic>Methods<\/jats:italic>. A retrospective review of diagnostic ERCPs in patients with OLT from 2002 to 2013 from a prospectively maintained, IRB approved database. <jats:italic>Results<\/jats:italic>. Of the 474 ERCPs performed in OLT patients, 210 (44.3%; 95% CI 39.8\u201348.8) were performed for abnormal liver function tests during the study period. Majority of patients were Caucasian (83.8%), male (62.4%) with median age of 55 years (IQR 48\u201362 years). Biliary cannulation was successful in 99.6% of cases and findings included stricture in 45 (21.4 %); biliary stones\/sludge in 23 (11%); biliary dilation alone in 31 (14.8%); and normal in 91 (43.3%). Three (1.4%) patients developed mild, self-limiting pancreatitis; one patient (0.5%) developed cholangitis and two (1%) had postsphincterotomy bleeding. Multivariate analyses showed significant association between dilated ducts on imaging with a therapeutic outcome. <jats:italic>Conclusion<\/jats:italic>. Diagnostic ERCP in OLT patients presenting with liver function test abnormalities is safe and frequently therapeutic.<\/jats:p>","DOI":"10.1155\/2014\/314927","type":"journal-article","created":{"date-parts":[[2014,7,9]],"date-time":"2014-07-09T21:02:43Z","timestamp":1404939763000},"page":"1-5","source":"Crossref","is-referenced-by-count":2,"title":["Safety and Yield of Diagnostic ERCP in Liver Transplant Patients with Abnormal Liver Function Tests"],"prefix":"10.1155","volume":"2014","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6573-1371","authenticated-orcid":true,"given":"Jayapal","family":"Ramesh","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Endoscopic Ultrasonography, Basil Hirschowitz Endoscopic Center of Excellence, University of Alabama at Birmingham, BDB 389, 1808 7th Avenue South, Birmingham, AL 35294, USA"},{"name":"Division of Gastroenterology and Hepatology, University of Alabama at Birmingham, Birmingham, AL 32803, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nipun","family":"Reddy","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, University of Alabama at Birmingham, Birmingham, AL 32803, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hwasoon","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, University of Alabama at Birmingham, Birmingham, AL 32803, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus","family":"M\u00f6nkem\u00fcller","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, University of Alabama at Birmingham, Birmingham, AL 32803, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shyam","family":"Varadarajulu","sequence":"additional","affiliation":[{"name":"Center for Interventional Endoscopy, Florida Hospital, Orlando, FL 35294, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brendan","family":"McGuire","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, University of Alabama at Birmingham, Birmingham, AL 32803, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8053-9695","authenticated-orcid":true,"given":"Derek","family":"DuBay","sequence":"additional","affiliation":[{"name":"Department of Liver Transplantation Surgery, University of Alabama at Birmingham, Birmingham, AL  32803, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2621-1431","authenticated-orcid":true,"given":"Devin","family":"Eckhoff","sequence":"additional","affiliation":[{"name":"Department of Liver Transplantation Surgery, University of Alabama at Birmingham, Birmingham, AL  32803, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. 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