{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T16:29:52Z","timestamp":1664382592356},"reference-count":30,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Otolaryngology"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. Endolymphatic sac tumor (ELST) is a rare neoplasm arising from the intrapetrous portion of the endolymphatic sac, either isolated or in association with the von Hippel-Lindau disease. We report a sporadic case of ELST with an overview of the literature and a discussion of clinic-radiological, histopathologic, and surgical findings.<jats:italic>Case Report<\/jats:italic>. A young woman presented with a progressive hearing loss in the left ear. Otoscopy showed a reddish, bleeding hypotympanic mass. CT demonstrated an expansile lytic mastoid lesion extending to the middle ear, with bone erosion. MRI confirmed a lesion of increased signal on T1-weighted sequences. The patient underwent a canal wall-down tympanoplasty with complete removal of the tumor. Histopathology was consistent with a papillary ELST. Immunohistochemistry was positive for cytokeratin and chromogranin A.<jats:italic>Conclusion<\/jats:italic>. This paper highlights the rarity of ELST, the need for an accurate neuroradiological and immunohistochemical study at the early stages, and the timeliness of surgical treatment.<\/jats:p>","DOI":"10.1155\/2014\/376761","type":"journal-article","created":{"date-parts":[[2014,6,4]],"date-time":"2014-06-04T17:05:02Z","timestamp":1401901502000},"page":"1-6","source":"Crossref","is-referenced-by-count":4,"title":["A Rare Case of Endolymphatic Sac Tumour: Clinicopathologic Study and Surgical Management"],"prefix":"10.1155","volume":"2014","author":[{"given":"Emanuele","family":"Ferri","sequence":"first","affiliation":[{"name":"Emergency Department, Otorhinolaryngology Unit, Otosurgery and Audiovestibology Section, General Hospital of Monselice, Via G. 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