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Inflammatory mediators are thought to be involved in the systemic and local immune response induced by<jats:italic>Tityus serrulatus<\/jats:italic>scorpion envenomation. The aim of this study was to evaluate the effect of extracts of<jats:italic>Mimosa tenuiflora<\/jats:italic>on model envenomation. In mice, the envenomation model is induced by<jats:italic>Tityus serrulatus<\/jats:italic>venom. Previous treatment of mice with fractions from<jats:italic>M. tenuiflora<\/jats:italic>was able to suppress the cell migration to the peritoneal cavity. The treatment of mice with<jats:italic>M. tenuiflora<\/jats:italic>extracts also decreased the levels of IL-6, IL-12, and IL-1<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>\u03b2<\/mml:mi><\/mml:mrow><\/mml:math>. We concluded that the administration of the extract and fractions resulted in a reduction in cell migration and showed a reduction in the level of proinflammatory cytokines. This study demonstrates, for the first time, the anti-inflammatory effect of aqueous extract from the<jats:italic>Mimosa tenuiflora<\/jats:italic>plant on<jats:italic>T. serrulatus<\/jats:italic>venom.<\/jats:p>","DOI":"10.1155\/2014\/378235","type":"journal-article","created":{"date-parts":[[2014,6,11]],"date-time":"2014-06-11T21:21:54Z","timestamp":1402521714000},"page":"1-8","source":"Crossref","is-referenced-by-count":10,"title":["Neutralizing Effects of<i>Mimosa tenuiflora<\/i>Extracts against Inflammation Caused by<i>Tityus serrulatus<\/i>Scorpion Venom"],"prefix":"10.1155","volume":"2014","author":[{"given":"Mariana Ang\u00e9lica Oliveira","family":"Bitencourt","sequence":"first","affiliation":[{"name":"Laboratory of Pharmaceutical Technology and Biotechnology, Department of Pharmacy, Federal University of Rio Grande do Norte, Avenue General Gustavo Cordeiro de Farias, Petr\u00f3polis, 59012-570 Natal, RN, 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