{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T21:34:25Z","timestamp":1772228065561,"version":"3.50.1"},"reference-count":21,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Pathology"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>The presence of signet-ring cells in an endometrial adenocarcinoma is extremely uncommon and it is always necessary to rule out a metastatic neoplasm. We report a FIGO grade 2 endometrial carcinoma with a signet-ring cell component found in the curettage performed to a 53-year-old woman. The neoplastic proliferation was also found in the endometrium of the radical hysterectomy with bilateral salpingo-oophorectomy and pelvic and para-aortic lymphadenectomy. The uterine neoplasm invaded less than one-half of the myometrium (FIGO stage I B). Alcian blue showed the presence of mucin in the signet-ring cells. The patient was alive and without evidence of recurrence 14 months after surgery. Polymerase chain reaction method from paraffin-embedded tissue revealed the presence of human papilloma virus type 11. We have discussed the differential diagnosis of this kind of neoplasm and we have reviewed the literature on signet-ring cell carcinoma of the endometrium.<\/jats:p>","DOI":"10.1155\/2014\/380571","type":"journal-article","created":{"date-parts":[[2014,4,7]],"date-time":"2014-04-07T23:05:40Z","timestamp":1396911940000},"page":"1-6","source":"Crossref","is-referenced-by-count":4,"title":["HPV11 Positive Endometrioid Carcinoma of the Endometrium with Signet-Ring Cells: Diagnostic Criteria and Review of the Literature"],"prefix":"10.1155","volume":"2014","author":[{"given":"Teresa","family":"Pusiol","sequence":"first","affiliation":[{"name":"Institute of Anatomic Pathology, Rovereto Hospital, Rovereto, 38060 Trento, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"issue":"2","key":"1","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1097\/00004347-199704000-00014","volume":"16","year":"1997","journal-title":"International Journal of Gynecological Pathology"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1097\/PGP.0b013e3181c1cbf2"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1097\/PGP.0b013e3181e20c66"},{"key":"4","series-title":"World Health Organization Classification of Tumours","first-page":"272","volume-title":"Epithelial tumours","year":"2003"},{"key":"5","series-title":"World Health Organization Classification of Tumours","first-page":"221","volume-title":"Epithelial tumours and related lesions","year":"2003"},{"key":"6","first-page":"517","volume-title":"Adenocarcinoma, carcinosarcoma, and other epithelial tumors of the endometrium","year":"2006"},{"issue":"2","key":"7","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1097\/00004347-198302000-00004","volume":"2","year":"1983","journal-title":"International Journal of Gynecological Pathology"},{"issue":"10","key":"8","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1002\/1097-0142(19821115)50:10<2163::AID-CNCR2820501032>3.0.CO;2-F","volume":"50","year":"1982","journal-title":"Cancer"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-08-3301"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/s12032-010-9416-4"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/S0929-6646(08)60138-2"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1155\/2007\/60549"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1097\/PGP.0b013e3181b8e951"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200402000-00002"},{"issue":"1","key":"15","first-page":"104","volume":"87","year":"2008","journal-title":"Gynecologic Oncology"},{"issue":"2","key":"16","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1097\/IGC.0b013e31825cc8ee","volume":"23","year":"2013","journal-title":"International Journal of Gynecological Cancer"},{"issue":"3, article 597","key":"17","volume":"30","year":"2013","journal-title":"Medical Oncology"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1097\/01.PGP.0000055172.04957.2F"},{"issue":"6","key":"19","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1016\/S0002-9440(10)65689-1","volume":"153","year":"1998","journal-title":"American Journal of Pathology"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2011.05.010"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2012.103"}],"container-title":["Case Reports in Pathology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripa\/2014\/380571.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripa\/2014\/380571.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cripa\/2014\/380571.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,22]],"date-time":"2017-06-22T11:10:21Z","timestamp":1498129821000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/cripa\/2014\/380571\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":21,"alternative-id":["380571","380571"],"URL":"https:\/\/doi.org\/10.1155\/2014\/380571","relation":{},"ISSN":["2090-6781","2090-679X"],"issn-type":[{"value":"2090-6781","type":"print"},{"value":"2090-679X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}