{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T06:51:44Z","timestamp":1763967104107},"reference-count":9,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"Comisi\u00f3n de Equidad y G\u00e9nero de la Honorable C\u00e1mara de Diputados de la LXI Legislatura de M\u00e9xico"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>Due to the lack of therapeutic options for patients with progressive multifocal leukoencephalopathy-associated immune reconstitution inflammatory syndrome (PML-associated IRIS), maraviroc has generated expectations among the medical community. However, we report a patient with advanced HIV infection, who developed PML-associated IRIS and had a fatal outcome despite the addition of maraviroc to suppressive ART. Future studies are required to define the therapeutic role of maraviroc in PML-associated IRIS and differentiate individuals who may benefit from maraviroc from those who may develop neurological deterioration.<\/jats:p>","DOI":"10.1155\/2014\/381480","type":"journal-article","created":{"date-parts":[[2014,12,23]],"date-time":"2014-12-23T21:58:46Z","timestamp":1419371926000},"page":"1-3","source":"Crossref","is-referenced-by-count":9,"title":["Maraviroc Failed to Control Progressive Multifocal Leukoencephalopathy-Associated IRIS in a Patient with Advanced HIV Infection"],"prefix":"10.1155","volume":"2014","author":[{"given":"M\u00f3nica","family":"Rodr\u00edguez","sequence":"first","affiliation":[{"name":"Centro de Investigaci\u00f3n en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias Ismael Cos\u00edo Villegas, Calzada de Tlalpan 4502, Colonia Secci\u00f3n XVI, 14080 M\u00e9xico, DF, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando Antonio","family":"Silva-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias Ismael Cos\u00edo Villegas, Calzada de Tlalpan 4502, Colonia Secci\u00f3n XVI, 14080 M\u00e9xico, DF, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9sar","family":"Luna-Rivero","sequence":"additional","affiliation":[{"name":"Servicio de Patolog\u00eda, Instituto Nacional de Enfermedades Respiratorias Ismael Cos\u00edo Villegas, 14080 M\u00e9xico, DF, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo","family":"Vega-Barrientos","sequence":"additional","affiliation":[{"name":"Servicio Cl\u00ednico 4, Instituto Nacional de Enfermedades Respiratorias Ismael Cos\u00edo Villegas, 14080 M\u00e9xico, DF, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Alvarado-de la Barrera","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias Ismael Cos\u00edo Villegas, Calzada de Tlalpan 4502, Colonia Secci\u00f3n XVI, 14080 M\u00e9xico, DF, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo","family":"Reyes-Ter\u00e1n","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n en Enfermedades Infecciosas, Instituto Nacional de Enfermedades Respiratorias Ismael Cos\u00edo Villegas, Calzada de Tlalpan 4502, Colonia Secci\u00f3n XVI, 14080 M\u00e9xico, DF, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.710"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/s1473-3099(09)70226-9"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1097\/qad.0b013e32833365f4"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1056\/nejmc1304828"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1086\/649426"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1086\/524709"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1001\/jama.296.7.815"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.0b013e3182768983"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jit388"}],"container-title":["Case Reports in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2014\/381480.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2014\/381480.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2014\/381480.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,18]],"date-time":"2016-08-18T18:06:08Z","timestamp":1471543568000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crim\/2014\/381480\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":9,"alternative-id":["381480","381480"],"URL":"https:\/\/doi.org\/10.1155\/2014\/381480","relation":{},"ISSN":["1687-9627","1687-9635"],"issn-type":[{"value":"1687-9627","type":"print"},{"value":"1687-9635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}