{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T01:26:16Z","timestamp":1648862776574},"reference-count":12,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>The present review describes and validates a new ratio \u201c<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>S<\/mml:mi><\/mml:mrow><\/mml:math>\u201d created for matching predictability and balance between TP and TN. Validity of<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>S<\/mml:mi><\/mml:mrow><\/mml:math>was studied in a three-step process as follows: (i)<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mrow><mml:mi>S<\/mml:mi><\/mml:mrow><\/mml:math>was applied to the data of a past study predicting cardiac output response to fluid bolus from response to passive leg raise (PLR); (ii)<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mrow><mml:mi>S<\/mml:mi><\/mml:mrow><\/mml:math>was comparatively analyzed with traditional ratios by modeling different 2 * 2 contingency tables in 1000 hypothetical patients; (iii) precision of<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mrow><mml:mi>S<\/mml:mi><\/mml:mrow><\/mml:math>was compared with other ratios by computing random fluctuations in the same patients. In comparison to other ratios,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mrow><mml:mi>S<\/mml:mi><\/mml:mrow><\/mml:math>performs better in predicting the cardiac response to fluid bolus and supports more directly the clinical conclusions. When the proportion of false responses is high,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mrow><mml:mi>S<\/mml:mi><\/mml:mrow><\/mml:math>is close to the coefficient correlation (CC). When the proportion of true responses is high,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\"><mml:mrow><mml:mi>S<\/mml:mi><\/mml:mrow><\/mml:math>is the unique ratio that identifies the categorization that balances the proportion of TP and TN. The precision of<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M9\"><mml:mrow><mml:mi>S<\/mml:mi><\/mml:mrow><\/mml:math>is close to that of CC. In conclusion,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M10\"><mml:mrow><mml:mi>S<\/mml:mi><\/mml:mrow><\/mml:math>should be considered for creating categories from quantitative variables; especially when matching predictability with balance between TP and TN is a concern.<\/jats:p>","DOI":"10.1155\/2014\/389845","type":"journal-article","created":{"date-parts":[[2014,3,9]],"date-time":"2014-03-09T05:20:55Z","timestamp":1394342455000},"page":"1-8","source":"Crossref","is-referenced-by-count":0,"title":["A New Ratio for Protocol Categorization"],"prefix":"10.1155","volume":"2014","author":[{"given":"Pierre","family":"Squara","sequence":"first","affiliation":[{"name":"CERIC, Clinique Ambroise Par\u00e9, 27 boulevard Victor Hugo, 92200 Neuilly-sur-Seine, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"issue":"5","key":"1","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1093\/bioinformatics\/16.5.412","volume":"16","year":"2000","journal-title":"Bioinformatics"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1186\/cc5044"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000215453.11735.06"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2012-001667"},{"key":"5","year":"2006"},{"issue":"2","key":"6","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/0005-2795(75)90109-9","volume":"405","year":"1975","journal-title":"Biochimica et Biophysica Acta"},{"issue":"1","key":"7","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1148\/radiology.143.1.7063747","volume":"143","year":"1982","journal-title":"Radiology"},{"issue":"2","key":"8","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1177\/0272989X8400400203","volume":"4","year":"1984","journal-title":"Medical Decision Making"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-010-1990-6"},{"key":"10","first-page":"390","volume-title":"RxC cintingency tables","year":"2006"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00096.2010"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-004-2449-4"}],"container-title":["Computational and Mathematical Methods in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2014\/389845.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2014\/389845.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2014\/389845.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,22]],"date-time":"2017-06-22T05:17:17Z","timestamp":1498108637000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/cmmm\/2014\/389845\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":12,"alternative-id":["389845","389845"],"URL":"https:\/\/doi.org\/10.1155\/2014\/389845","relation":{},"ISSN":["1748-670X","1748-6718"],"issn-type":[{"value":"1748-670X","type":"print"},{"value":"1748-6718","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}