{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:26:15Z","timestamp":1759332375761,"version":"3.37.3"},"reference-count":29,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,1,22]],"date-time":"2014-01-22T00:00:00Z","timestamp":1390348800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ISRN Ophthalmology"],"published-print":{"date-parts":[[2014,1,22]]},"abstract":"<jats:p><jats:italic>Purpose<\/jats:italic>. To evaluate the visual outcomes and effect of phacoemulsification surgery on the progression of neovascular age-related macular degeneration (AMD). <jats:italic>Methods<\/jats:italic>. Retrospective, noncomparative, and interventional case series. Thirty eyes from 29 subjects with neovascular AMD treated with intravitreal antivascular endothelial growth factor (VEGF) injections who underwent phacoemulsification and had a postsurgery follow-up of 6 months were included. LogMAR best corrected visual acuity (BCVA) was assessed preoperatively; 1 month, 3 months, and 6 months postoperatively; and finally at the last visit. The frequency of anti-VEGF therapy, calculated as the number of intravitreal injections per month, and central macular thickness (CMT) before and after cataract surgery were determined. <jats:italic>Results<\/jats:italic>. Median (range) logMAR BCVA was 0.69 (0.16 to 1.32) preoperatively; 0.55 (\u22120.04 to 1.32) at 1 month, 0.52 (\u22120.1 to 1.32) at 3 months, and 0.50 (0.0 to 1.32) at 6 months postoperatively; and 0.6 (0.0 to 1.4) at final visit (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.0011<\/mml:mn><\/mml:math>). There was no difference in the frequency of anti-VEGF injections between the immediate 6 months before and after phacoemulsification, which was equal to 0.1667 injections per month (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.6377<\/mml:mn><\/mml:math>). Median CMT measured 203\u2009<jats:italic>\u03bc<\/jats:italic>m preoperatively, which temporarily increased to 238\u2009<jats:italic>\u03bc<\/jats:italic>m at 1 month after surgery (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.0093<\/mml:mn><\/mml:math>) and then spontaneously returned to baseline, measuring 212.5\u2009<jats:italic>\u03bc<\/jats:italic>m at 3 months postoperatively (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.3811<\/mml:mn><\/mml:math>). <jats:italic>Conclusion<\/jats:italic>. Phacoemulsification surgery significantly improved vision in patients with neovascular AMD, with no increased need for anti-VEGF injections to keep the macula dry postoperatively.<\/jats:p>","DOI":"10.1155\/2014\/417603","type":"journal-article","created":{"date-parts":[[2014,1,23]],"date-time":"2014-01-23T06:27:02Z","timestamp":1390458422000},"page":"1-6","source":"Crossref","is-referenced-by-count":21,"title":["Phacoemulsification Surgery in Eyes with Neovascular Age-Related Macular Degeneration"],"prefix":"10.1155","volume":"2014","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1767-6467","authenticated-orcid":true,"given":"Andre","family":"Grixti","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Wirral University Teaching Hospital, Arrowe Park Road, Wirral, Merseyside CH49 5PE, UK"},{"name":"Department of Ophthalmology, St. Paul\u2019s Eye Unit, Royal Liverpool University Hospital, Prescot Street, Liverpool, Merseyside L7 8XP, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evangelia","family":"Papavasileiou","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Wirral University Teaching Hospital, Arrowe Park Road, Wirral, Merseyside CH49 5PE, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6376-9824","authenticated-orcid":true,"given":"Dominic","family":"Cortis","sequence":"additional","affiliation":[{"name":"Department of Mathematics, University of Leicester, University Road, Leicester LE1 7RH, UK"},{"name":"The Insurance Unit, Faculty of Economics, Management and Accountancy, University of Malta, Msida, MSD2080, Malta"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Balakrishna Vineeth","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Wirral University Teaching Hospital, Arrowe Park Road, Wirral, Merseyside CH49 5PE, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Som","family":"Prasad","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Wirral University Teaching Hospital, Arrowe Park Road, Wirral, Merseyside CH49 5PE, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"1","key":"1","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0002-9394(79)90195-8","volume":"87","year":"1979","journal-title":"American Journal of Ophthalmology"},{"issue":"10","key":"2","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1016\/S0161-6420(96)30464-8","volume":"103","year":"1996","journal-title":"Ophthalmology"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2006.10.019"},{"issue":"11","key":"4","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1001\/archopht.120.11.1551","volume":"120","year":"2002","journal-title":"Archives of 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