{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T13:04:11Z","timestamp":1773320651504,"version":"3.50.1"},"reference-count":11,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pregnancy"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. To evaluate factor XII levels in women with recurrent pregnancy loss (RPL) in a tertiary referral hospital.<jats:italic>Methods<\/jats:italic>. Women who were referred to our hospital for two consecutive abortions or three abortions in between 2007 and 2013 were included in this retrospective observational study. Women were further grouped according to factor XII levels, as &lt;60% and \u226560%.<jats:italic>Results<\/jats:italic>. Mean factor XII level was 109.1 \u00b1 35.7% (range: 9\u2013200). Ninety-three (7.4%) women had factor XII levels &lt; 60%. Mean factor XII level was 44.8 \u00b1 13.1, and levels ranged between 9 and 60 in this group. Only one woman had factor XII level &lt; 10 %. Remaining 1164 (92.6%) women had factor XII levels \u2265 60%. Mean factor XII level was 114.3 \u00b1 31.7, and levels ranged between 60.3 and 200 in this group, while 1015 (72.4%) women had factor XII levels within the normal range (60%\u2013150% [100% = 30\u2009<jats:italic>\u03bc<\/jats:italic>g\/mL]).<jats:italic>Conclusion<\/jats:italic>. Decreased activity of F-XII was diagnosed in 7.4% of women with RPL. We concluded factor XII deficiency that might be a rare but significant factor for RPL, and should be evaluated in women who are investigated for recurrent pregnancy loss.<\/jats:p>","DOI":"10.1155\/2014\/459192","type":"journal-article","created":{"date-parts":[[2014,11,12]],"date-time":"2014-11-12T16:02:17Z","timestamp":1415808137000},"page":"1-3","source":"Crossref","is-referenced-by-count":12,"title":["Factor XII (Hageman) Levels in Women with Recurrent Pregnancy Loss"],"prefix":"10.1155","volume":"2014","author":[{"given":"A. Seval","family":"Ozgu-Erdinc","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Zekai Tahir Burak Women\u2019s Health Care, Training and Research Hospital, Talatpasa Bulvari, 06230 Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cihan","family":"Togrul","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Diyarbak\u0131r Women\u2019s Health and Children Disease Hospital, Diyarbak\u0131r, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayla","family":"Aktulay","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Zekai Tahir Burak Women\u2019s Health Care, Training and Research Hospital, Talatpasa Bulvari, 06230 Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umran","family":"Buyukkagnici","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Zekai Tahir Burak Women\u2019s Health Care, Training and Research Hospital, Talatpasa Bulvari, 06230 Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elif Gul","family":"Yapar Eyi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Zekai Tahir Burak Women\u2019s Health Care, Training and Research Hospital, Talatpasa Bulvari, 06230 Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salim","family":"Erkaya","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Zekai Tahir Burak Women\u2019s Health Care, Training and Research Hospital, Talatpasa Bulvari, 06230 Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.12110"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1160\/TH07-07-0447"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(03)00788-X"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1078\/0171-2985-00207"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000260873.94196.d6"},{"issue":"1-2","key":"6","first-page":"56","volume":"59","year":"2014","journal-title":"Journal of Reproductive Medicine"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1055\/s-2001-14070"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1159\/000010220"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0897.2007.00564.x"},{"issue":"1","key":"10","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/S0015-0282(16)55622-2","volume":"59","year":"1993","journal-title":"Fertility and Sterility"},{"issue":"6","key":"11","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1055\/s-0038-1656119","volume":"77","year":"1997","journal-title":"Thrombosis and Haemostasis"}],"container-title":["Journal of Pregnancy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/jp\/2014\/459192.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jp\/2014\/459192.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jp\/2014\/459192.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,17]],"date-time":"2019-08-17T04:33:36Z","timestamp":1566016416000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/jp\/2014\/459192\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":11,"alternative-id":["459192","459192"],"URL":"https:\/\/doi.org\/10.1155\/2014\/459192","relation":{},"ISSN":["2090-2727","2090-2735"],"issn-type":[{"value":"2090-2727","type":"print"},{"value":"2090-2735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}