{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T16:48:34Z","timestamp":1776703714833,"version":"3.51.2"},"reference-count":152,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"name":"The Royal Brisbane Women\u2019s Hospital (RBWH) Foundation"},{"DOI":"10.13039\/501100001078","name":"Queensland Emergency Medicine Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001078","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001203","name":"GlaxoSmithKline Australia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001203","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Australian Red Cross Blood Service"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>Animal models of critical illness are vital in biomedical research. They provide possibilities for the investigation of pathophysiological processes that may not otherwise be possible in humans. In order to be clinically applicable, the model should simulate the critical care situation realistically, including anaesthesia, monitoring, sampling, utilising appropriate personnel skill mix, and therapeutic interventions. There are limited data documenting the constitution of ideal technologically advanced large animal critical care practices and all the processes of the animal model. In this paper, we describe the procedure of animal preparation, anaesthesia induction and maintenance, physiologic monitoring, data capture, point-of-care technology, and animal aftercare that has been successfully used to study several novel ovine models of critical illness. The relevant investigations are on respiratory failure due to smoke inhalation, transfusion related acute lung injury, endotoxin-induced proteogenomic alterations, haemorrhagic shock, septic shock, brain death, cerebral microcirculation, and artificial heart studies. We have demonstrated the functionality of monitoring practices during anaesthesia required to provide a platform for undertaking systematic investigations in complex ovine models of critical illness.<\/jats:p>","DOI":"10.1155\/2014\/468309","type":"journal-article","created":{"date-parts":[[2014,3,27]],"date-time":"2014-03-27T07:24:43Z","timestamp":1395905083000},"page":"1-17","source":"Crossref","is-referenced-by-count":22,"title":["Optimal Management of the Critically Ill: Anaesthesia, Monitoring, Data Capture, and Point-of-Care Technological Practices in Ovine Models of Critical Care"],"prefix":"10.1155","volume":"2014","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7206-137X","authenticated-orcid":true,"given":"Saul","family":"Chemonges","sequence":"first","affiliation":[{"name":"Critical Care Research Group Laboratory, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD 4032, Australia"},{"name":"The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia"},{"name":"Medical Engineering Research Facility (MERF), Queensland University of Technology, Brisbane, QLD 4001, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiran","family":"Shekar","sequence":"additional","affiliation":[{"name":"Critical Care Research Group Laboratory, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD 4032, Australia"},{"name":"The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia"},{"name":"Bond University, Gold Coast, QLD 4226, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John-Paul","family":"Tung","sequence":"additional","affiliation":[{"name":"Critical Care Research Group Laboratory, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD 4032, Australia"},{"name":"Research and Development, Australian Red Cross Blood Service, Kelvin Grove, Brisbane, QLD 4059, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimble R.","family":"Dunster","sequence":"additional","affiliation":[{"name":"Critical Care Research Group Laboratory, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD 4032, Australia"},{"name":"Science and Engineering Faculty, Queensland University of Technology, Brisbane, QLD 4001, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4743-6787","authenticated-orcid":true,"given":"Sara","family":"Diab","sequence":"additional","affiliation":[{"name":"Critical Care Research Group Laboratory, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD 4032, Australia"},{"name":"The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Platts","sequence":"additional","affiliation":[{"name":"Critical Care Research Group Laboratory, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD 4032, Australia"},{"name":"The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan P.","family":"Watts","sequence":"additional","affiliation":[{"name":"Critical Care Research Group Laboratory, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD 4032, Australia"},{"name":"Department of Emergency Medicine, Princess Alexandra Hospital, 199 Ipswich Road, Woolloongabba, QLD 4102, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaun D.","family":"Gregory","sequence":"additional","affiliation":[{"name":"Critical Care Research Group Laboratory, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD 4032, Australia"},{"name":"The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia"},{"name":"Innovative Cardiovascular Engineering and Technology Laboratory, The Prince Charles Hospital, Chermside, Brisbane, QLD 4032, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9346-7456","authenticated-orcid":true,"given":"Samuel","family":"Foley","sequence":"additional","affiliation":[{"name":"Critical Care Research Group Laboratory, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD 4032, Australia"},{"name":"The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela","family":"Simonova","sequence":"additional","affiliation":[{"name":"Critical Care Research Group Laboratory, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD 4032, Australia"},{"name":"The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"McDonald","sequence":"additional","affiliation":[{"name":"Critical Care Research Group Laboratory, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD 4032, Australia"},{"name":"The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rylan","family":"Hayes","sequence":"additional","affiliation":[{"name":"Critical Care Research Group Laboratory, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD 4032, Australia"},{"name":"The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith","family":"Bellpart","sequence":"additional","affiliation":[{"name":"Critical Care Research Group Laboratory, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD 4032, Australia"},{"name":"The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Timms","sequence":"additional","affiliation":[{"name":"Critical Care Research Group Laboratory, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD 4032, Australia"},{"name":"Innovative Cardiovascular Engineering and Technology Laboratory, The Prince Charles Hospital, Chermside, Brisbane, QLD 4032, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2888-4111","authenticated-orcid":true,"given":"Michelle","family":"Chew","sequence":"additional","affiliation":[{"name":"Critical Care Research Group Laboratory, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD 4032, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoke L.","family":"Fung","sequence":"additional","affiliation":[{"name":"Critical Care Research Group Laboratory, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD 4032, Australia"},{"name":"The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Toon","sequence":"additional","affiliation":[{"name":"Critical Care Research Group Laboratory, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD 4032, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc O.","family":"Maybauer","sequence":"additional","affiliation":[{"name":"Critical Care Research Group Laboratory, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD 4032, Australia"},{"name":"The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John F.","family":"Fraser","sequence":"additional","affiliation":[{"name":"Critical Care Research Group Laboratory, The Prince Charles Hospital, Rode Road, Chermside, Brisbane, QLD 4032, Australia"},{"name":"The University of Queensland, St Lucia, Brisbane, QLD 4072, Australia"},{"name":"Innovative Cardiovascular Engineering and Technology Laboratory, The Prince Charles Hospital, Chermside, Brisbane, QLD 4032, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/01.shk.0000191338.39154.73"},{"issue":"2","key":"2","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S1441-2772(23)01583-1","volume":"14","year":"2012","journal-title":"Critical Care and Resuscitation"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1038\/nri977"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2011.06345.x"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1293\/tox.20.125"},{"issue":"1","key":"6","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1196\/annals.1334.015","volume":"1049","year":"2005","journal-title":"Annals of the New York Academy of Sciences"},{"issue":"2","key":"7","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/S0195-5616(92)50658-1","volume":"22","year":"1992","journal-title":"Veterinary Clinics of North America\u2014Small Animal Practice"},{"issue":"2","key":"8","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/S0195-5616(92)50659-3","volume":"22","year":"1992","journal-title":"Veterinary Clinics of North America\u2014Small Animal Practice"},{"key":"9","first-page":"63","volume-title":"Monitoring the critical patient","year":"2012"},{"key":"10","year":"1996"},{"key":"11","year":"1991"},{"key":"12","first-page":"936","volume":"206","year":"1995","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1097\/MAT.0b013e31824cc856"},{"key":"14","volume":"12, article 29","year":"2012","journal-title":"BMC Anesthesiology"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks435"},{"key":"16","volume":"2, article 2","year":"2014","journal-title":"Intensive Care Medicine Experimental"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.2010.01381.x"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1186\/cc11178"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2172-10-25"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12032"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2008.11.048"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1594.2011.01283.x"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1594.2008.00633.x"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1594.2011.01344.x"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.01635.2005"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2008.11.028"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/521369"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/595838"},{"issue":"1","key":"29","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1177\/0023677212473712","volume":"47","year":"2013","journal-title":"Laboratory Animals"},{"issue":"2","key":"30","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1467-2995.2012.00772.x","volume":"40","year":"2013","journal-title":"Veterinary Anaesthesia and Analgesia"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1080\/00480169.2011.645769"},{"issue":"2","key":"32","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1111\/1471-0528.12081","volume":"120","year":"2013","journal-title":"BJOG"},{"issue":"5","key":"33","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1097\/SHK.0b013e31826e9c54","volume":"38","year":"2012","journal-title":"Shock"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2012.01.003"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0b013e31823ca8ee"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e31820b8b44"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1186\/cc10016"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2010.12.011"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2010.11.005"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181feb802"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0b013e3181eb4556"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2009.02471.x"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2009.05.016"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2010.01.009"},{"key":"45","doi-asserted-by":"publisher","DOI":"10.1186\/cc9342"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1007\/s00540-009-0763-2"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2009.01.003"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2008.12.013"},{"key":"49","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0b013e3181a4fd01"},{"key":"50","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2007.00358.x"},{"key":"51","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-008-0664-0"},{"key":"52","doi-asserted-by":"publisher","DOI":"10.1213\/ane.0b013e31816d12af"},{"key":"53","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31816a1a0c"},{"key":"54","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2008.10.066"},{"key":"55","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000263274.62303.1a"},{"key":"56","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-007-0658-3"},{"key":"57","doi-asserted-by":"publisher","DOI":"10.1016\/j.pupt.2006.03.010"},{"key":"58","doi-asserted-by":"publisher","DOI":"10.1016\/j.pupt.2006.03.003"},{"key":"59","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00504.2006"},{"key":"60","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2006.04.001"},{"key":"61","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200607000-00015"},{"key":"62","doi-asserted-by":"publisher","DOI":"10.1097\/01.BCR.0000216512.30415.78"},{"issue":"4","key":"63","first-page":"14","volume":"45","year":"2006","journal-title":"Journal of the American Association for Laboratory Animal Science"},{"key":"64","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2005.06.063"},{"key":"65","doi-asserted-by":"publisher","DOI":"10.1097\/01.shk.0000230300.78515.ed"},{"key":"66","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000230384.61350.FA"},{"key":"67","doi-asserted-by":"publisher","DOI":"10.1097\/01.shk.0000209525.50990.28"},{"key":"68","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000215828.00289.B9"},{"key":"69","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2004.074161"},{"key":"70","doi-asserted-by":"publisher","DOI":"10.1258\/0023677052886600"},{"key":"71","doi-asserted-by":"publisher","DOI":"10.1016\/j.resp.2005.05.023"},{"key":"72","doi-asserted-by":"publisher","DOI":"10.1016\/j.burns.2005.06.021"},{"key":"73","doi-asserted-by":"publisher","DOI":"10.1097\/01.shk.0000174021.95063.f4"},{"key":"74","doi-asserted-by":"publisher","DOI":"10.1097\/01.shk.0000150777.39484.b0"},{"key":"75","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200505000-00014"},{"key":"76","doi-asserted-by":"publisher","DOI":"10.1186\/cc11178"},{"key":"77","year":"2013"},{"key":"78","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.108.814459"},{"key":"79","doi-asserted-by":"publisher","DOI":"10.1186\/cc3099"},{"key":"80","doi-asserted-by":"publisher","DOI":"10.2478\/v10019-008-0004-6"},{"issue":"1","key":"81","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1053\/jvet.1999.0077","volume":"28","year":"1999","journal-title":"Veterinary Surgery"},{"issue":"1","key":"82","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1046\/j.1365-2885.1998.00104.x","volume":"21","year":"1998","journal-title":"Journal of Veterinary Pharmacology and Therapeutics"},{"issue":"2","key":"83","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1093\/bja\/80.2.208","volume":"80","year":"1998","journal-title":"British Journal of Anaesthesia"},{"issue":"1","key":"84","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1136\/inpract.13.1.31","volume":"13","year":"1991","journal-title":"In Practice"},{"issue":"9","key":"85","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1111\/j.1751-0813.2012.00974.x","volume":"90","year":"2012","journal-title":"Australian Veterinary Journal"},{"key":"86","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.2009.00390.x"},{"key":"87","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2011.10.003"},{"key":"88","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.2009.00401.x"},{"key":"89","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2011.03.017"},{"key":"90","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200005043421801"},{"key":"91","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000155782.86244.42"},{"key":"92","doi-asserted-by":"publisher","DOI":"10.1016\/j.rcc.2006.05.003"},{"key":"93","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2006.11.015"},{"key":"94","doi-asserted-by":"publisher","DOI":"10.1053\/eupc.2001.0204"},{"issue":"6","key":"95","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1136\/heart.87.6.529","volume":"87","year":"2002","journal-title":"Heart"},{"issue":"3","key":"96","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1136\/vr.149.3.80","volume":"149","year":"2001","journal-title":"The Veterinary Record"},{"key":"97","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1843.1999.00169.x"},{"issue":"4","key":"98","first-page":"277","volume":"7","year":"1989","journal-title":"Journal of Hypertension"},{"key":"99","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1017\/S0021859600086469","volume":"81","year":"1973","journal-title":"Journal of Agricultural Science"},{"key":"100","doi-asserted-by":"publisher","DOI":"10.1007\/s11259-010-9346-9"},{"key":"101","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2011.00614.x"},{"key":"102","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aei054"},{"key":"103","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/270631"},{"key":"104","year":"1995"},{"issue":"1","key":"105","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1046\/j.1467-2995.2003.00121.x","volume":"30","year":"2003","journal-title":"Veterinary Anaesthesia and Analgesia"},{"issue":"10","key":"106","first-page":"761","volume":"26","year":"2004","journal-title":"Compendium on Continuing Education for the Practicing Veterinarian"},{"issue":"1","key":"107","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/1475-925X-11-64","volume":"11","year":"2012","journal-title":"Biomedical Engineering Online"},{"key":"108","volume":"11, article 68","year":"2012","journal-title":"Biomedical Engineering Online"},{"key":"109","doi-asserted-by":"publisher","DOI":"10.1088\/0967-3334\/27\/11\/008"},{"key":"110","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-008-1324-0"},{"key":"111","doi-asserted-by":"publisher","DOI":"10.1088\/0967-3334\/30\/10\/008"},{"key":"112","doi-asserted-by":"publisher","DOI":"10.3109\/01902148.2010.501402"},{"issue":"2-3","key":"113","first-page":"i","volume":"7","year":"1999","journal-title":"Technology and Health Care"},{"key":"114","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-011-2197-1"},{"issue":"5","key":"115","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/s10877-012-9383-8","volume":"26","year":"2012","journal-title":"Journal of Clinical Monitoring and Computing"},{"key":"116","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-1097.2012.01153.x"},{"key":"117","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2006.03.101"},{"key":"118","doi-asserted-by":"publisher","DOI":"10.2165\/00128413-200213290-00001"},{"key":"119","doi-asserted-by":"publisher","DOI":"10.1186\/cc8380"},{"key":"120","doi-asserted-by":"publisher","DOI":"10.1186\/cc9134"},{"key":"121","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-409X(00)00106-X"},{"issue":"2","key":"122","first-page":"50","volume":"33","year":"2003","journal-title":"Australian Veterinary Practitioner"},{"issue":"1-2","key":"123","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1751-0813.2004.tb14646.x","volume":"82","year":"2004","journal-title":"Australian Veterinary Journal"},{"issue":"2","key":"124","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1111\/vox.12076","volume":"106","year":"2014","journal-title":"Vox Sanguinis"},{"key":"125","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.2010.01381.x"},{"issue":"4","key":"126","first-page":"256","volume":"27","year":"2005","journal-title":"Compendium on Continuing Education for the Practicing Veterinarian"},{"key":"127","doi-asserted-by":"publisher","DOI":"10.4037\/ccn2011595"},{"issue":"4","key":"128","first-page":"453","volume":"57","year":"2009","journal-title":"T\u00fcberk\u00fcloz ve Toraks"},{"key":"129","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000196083.45897.E9"},{"key":"130","doi-asserted-by":"publisher","DOI":"10.1097\/MCC.0b013e328011278d"},{"key":"131","doi-asserted-by":"publisher","DOI":"10.4037\/ccn2009612"},{"issue":"5","key":"132","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1111\/j.1476-4431.2011.00673.x","volume":"21","year":"2011","journal-title":"Journal of Veterinary Emergency and Critical Care"},{"key":"133","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2326-5-3"},{"key":"135","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2005.01104.x"},{"key":"136","doi-asserted-by":"publisher","DOI":"10.1186\/cc5836"},{"key":"137","doi-asserted-by":"publisher","DOI":"10.1097\/MBC.0b013e32830ef90c"},{"key":"138","doi-asserted-by":"publisher","DOI":"10.1159\/000322256"},{"key":"139","doi-asserted-by":"publisher","DOI":"10.1097\/MBC.0b013e32833113e9"},{"issue":"7, supplement","key":"140","first-page":"S13","volume":"109","year":"2012","journal-title":"The American Journal of Cardiology"},{"key":"141","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2010.01.269"},{"key":"142","doi-asserted-by":"publisher","DOI":"10.3109\/09537100903236462"},{"key":"143","doi-asserted-by":"publisher","DOI":"10.1080\/09537100600944277"},{"key":"144","doi-asserted-by":"publisher","DOI":"10.1080\/09537100701280654"},{"key":"145","doi-asserted-by":"publisher","DOI":"10.1186\/1477-5956-12-12"},{"issue":"3","key":"146","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.burns.2012.08.006","volume":"39","year":"2013","journal-title":"Burns"},{"issue":"3","key":"147","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1161\/01.CIR.34.3.391","volume":"34","year":"1966","journal-title":"Circulation"},{"key":"148","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8167.2006.00716.x"},{"issue":"5","key":"149","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1111\/j.1540-8175.1997.tb00755.x","volume":"14","year":"1997","journal-title":"Echocardiography"},{"issue":"4","key":"150","doi-asserted-by":"crossref","first-page":"H1150","DOI":"10.1152\/ajpheart.1999.276.4.H1150","volume":"276","year":"1999","journal-title":"American Journal of Physiology\u2014Heart and Circulatory Physiology"},{"issue":"3","key":"151","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1097\/00024382-199609000-00008","volume":"6","year":"1996","journal-title":"Shock"},{"key":"154","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2011.06.107"},{"key":"155","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1000412"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2014\/468309.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2014\/468309.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2014\/468309.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,25]],"date-time":"2024-05-25T11:40:19Z","timestamp":1716637219000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/bmri\/2014\/468309\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":152,"alternative-id":["468309","468309"],"URL":"https:\/\/doi.org\/10.1155\/2014\/468309","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}