{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:43:41Z","timestamp":1788871421148,"version":"build-2803163510"},"reference-count":46,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"Public Funds for Science of China","award":["2997\/B\/P01\/2009\/36"],"award-info":[{"award-number":["2997\/B\/P01\/2009\/36"]}]},{"name":"Public Funds for Science of China","award":["FNP\/Welcome\/02"],"award-info":[{"award-number":["FNP\/Welcome\/02"]}]},{"DOI":"10.13039\/501100001870","name":"Fundacja na rzecz Nauki Polskiej","doi-asserted-by":"publisher","award":["2997\/B\/P01\/2009\/36"],"award-info":[{"award-number":["2997\/B\/P01\/2009\/36"]}],"id":[{"id":"10.13039\/501100001870","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001870","name":"Fundacja na rzecz Nauki Polskiej","doi-asserted-by":"publisher","award":["FNP\/Welcome\/02"],"award-info":[{"award-number":["FNP\/Welcome\/02"]}],"id":[{"id":"10.13039\/501100001870","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>\n                    Oral inflammation, such as periodontitis, can lead to endothelial dysfunction, accelerated atherosclerosis, and vascular dysfunction. The relationship between vascular dysfunction and other common forms of oral infections such as denture-related stomatitis (DRS) is unknown. Similar risk factors predispose to both conditions including smoking, diabetes, age, and obesity. Accordingly, we aimed to investigate endothelial function and major vascular disease risk factors in 44 consecutive patients with dentures with clinical and microbiological features of DRS (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                      <mml:mi>n<\/mml:mi>\n                      <mml:mo>=<\/mml:mo>\n                      <mml:mn>20<\/mml:mn>\n                    <\/mml:math>\n                    ) and without DRS (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                      <mml:mi>n<\/mml:mi>\n                      <mml:mo>=<\/mml:mo>\n                      <mml:mn>24<\/mml:mn>\n                    <\/mml:math>\n                    ). While there was a tendency for higher occurrence of diabetes and smoking, groups did not differ significantly in respect to major vascular disease risk factors. Groups did not differ in main ambulatory blood pressure, total cholesterol, or even CRP. Importantly, flow mediated dilatation (FMD) was significantly lower in DRS than in non-DRS subjects, while nitroglycerin induced vasorelaxation (NMD) or intima-media thickness (IMT) was similar. Interestingly, while triglyceride levels were normal in both groups, they were higher in DRS subjects, although they did not correlate with either FMD or NMD.\n                    <jats:italic>Conclusions<\/jats:italic>\n                    . Denture related stomatitis is associated with endothelial dysfunction in elderly patients with dentures. This is in part related to the fact that diabetes and smoking increase risk of both DRS and cardiovascular disease.\n                  <\/jats:p>","DOI":"10.1155\/2014\/474016","type":"journal-article","created":{"date-parts":[[2014,6,22]],"date-time":"2014-06-22T02:22:51Z","timestamp":1403403771000},"page":"1-9","source":"Crossref","is-referenced-by-count":22,"title":["Denture-Related Stomatitis Is Associated with Endothelial Dysfunction"],"prefix":"10.1155","volume":"2014","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9759-011X","authenticated-orcid":true,"given":"Joanna","family":"Maci\u0105g","sequence":"first","affiliation":[{"name":"Department of Prophylaxis and Experimental Dentistry, Institute of Dentistry, Jagiellonian University Medical College, Cracow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grzegorz","family":"Osmenda","sequence":"additional","affiliation":[{"name":"Department of Internal and Agricultural Medicine, Jagiellonian University Medical College, Cracow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Nowakowski","sequence":"additional","affiliation":[{"name":"Department of Prophylaxis and Experimental Dentistry, Institute of Dentistry, Jagiellonian University Medical College, Cracow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grzegorz","family":"Wilk","sequence":"additional","affiliation":[{"name":"Department of Internal and Agricultural Medicine, Jagiellonian University Medical College, Cracow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Maci\u0105g","sequence":"additional","affiliation":[{"name":"Zbigniew \u017bak Voivodeship Dental Clinic, Cracow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz","family":"Miko\u0142ajczyk","sequence":"additional","affiliation":[{"name":"Department of Internal and Agricultural Medicine, Jagiellonian University Medical College, Cracow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4661-8773","authenticated-orcid":true,"given":"Ryszard","family":"Nosalski","sequence":"additional","affiliation":[{"name":"Department of Internal and Agricultural Medicine, Jagiellonian University Medical College, Cracow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Sagan","sequence":"additional","affiliation":[{"name":"Department of Internal and Agricultural Medicine, Jagiellonian University Medical College, Cracow, Poland"},{"name":"Institute of Cardiovascular and Medical Sciences, University of Glasgow, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena","family":"Filip","sequence":"additional","affiliation":[{"name":"Department of Internal and Agricultural Medicine, Jagiellonian University Medical College, Cracow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miros\u0142aw","family":"Dr\u00f3\u017cd\u017c","sequence":"additional","affiliation":[{"name":"Department of Internal and Agricultural Medicine, Jagiellonian University Medical College, Cracow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jolanta","family":"Loster","sequence":"additional","affiliation":[{"name":"Department of Dental Prosthetics, Institute of Dentistry at Jagiellonian University Medical Collage, Cracow, Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz J.","family":"Guzik","sequence":"additional","affiliation":[{"name":"Department of Internal and Agricultural Medicine, Jagiellonian University Medical College, Cracow, Poland"},{"name":"Institute of Cardiovascular and Medical Sciences, University of Glasgow, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Cze\u015bnikiewicz-Guzik","sequence":"additional","affiliation":[{"name":"Department of Prophylaxis and Experimental Dentistry, Institute of Dentistry, Jagiellonian University Medical College, Cracow, Poland"},{"name":"Institute of Cardiovascular and Medical Sciences, University of Glasgow, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"issue":"12","key":"1","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1177\/00220345990780120301","volume":"78","year":"1999","journal-title":"Journal of Dental Research"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2002.290312.x"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.4.544"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000085086.50957.22"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000051456.68470.C8"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa063186"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2013.1222"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/503754"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-849X.2011.00698.x"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1741-2358.2009.00359.x"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-010-9275-8"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.16.e139"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2010.06.015"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000713"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.2008.00445.x"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2012.06.009"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X2011007500104"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20070657"},{"issue":"1","key":"19","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1111\/j.1651-2227.1997.tb08834.x","volume":"86","year":"1997","journal-title":"Acta Paediatrica"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1186\/1758-5996-2-22"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00875.x"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2011.09.006"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2005.10.039"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1177\/154405910608501104"},{"issue":"8","key":"25","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.14219\/jada.archive.2009.0311","volume":"140","year":"2009","journal-title":"Journal of the American Dental Association"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-013-1156-3"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2012.05.007"},{"issue":"9","key":"28","first-page":"443","volume":"123","year":"2013","journal-title":"Polskie Archiwum Medycyny Wewnetrznej"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e32835fb8ec"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2011.305"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2012.110636"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1111\/1744-1609.12038"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2013.12.008"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1007\/s00424-010-0786-4"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000078603.90302.4A"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2006.12.003"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2005.10.002"},{"issue":"9","key":"38","doi-asserted-by":"crossref","first-page":"E85","DOI":"10.1161\/01.RES.86.9.e85","volume":"86","year":"2000","journal-title":"Circulation Research"},{"issue":"8","key":"41","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1111\/j.1348-0421.2007.tb03960.x","volume":"51","year":"2007","journal-title":"Microbiology and Immunology"},{"issue":"4","key":"42","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/S0022-3913(96)90036-0","volume":"75","year":"1996","journal-title":"Journal of Prosthetic Dentistry"},{"issue":"1","key":"39","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/j.1741-2358.2003.00032.x","volume":"20","year":"2003","journal-title":"Gerodontology"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-009-0149-4"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.2010.01343.x"},{"issue":"1","key":"44","first-page":"214","volume":"8","year":"2014","journal-title":"Journal of Clinical and Diagnostic Research"},{"key":"45","doi-asserted-by":"publisher","DOI":"10.4103\/0972-124X.107471"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/768237"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2014\/474016.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2014\/474016.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2014\/474016.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,22]],"date-time":"2017-06-22T11:21:57Z","timestamp":1498130517000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/bmri\/2014\/474016\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":46,"alternative-id":["474016","474016"],"URL":"https:\/\/doi.org\/10.1155\/2014\/474016","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}