{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T17:28:11Z","timestamp":1648574891561},"reference-count":28,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Dentistry"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>Fraser syndrome is a rare genetic malformation with an autosomal recessive pattern of inheritance and an incidence of consanguinity ranging from 15% to 25%. A 5-year-old male patient who is a carrier of Fraser syndrome initiated treatment in the pediatric dentistry sector. The patient was fed parenterally since birth, experienced recurring bouts of chronic lung disease, and was referred to the pediatric dentistry sector by the medical team. Radiographic examination revealed the presence of all permanent teeth. Supragingival dental calculus, halitosis, and gingival inflammation were also observed. Dental calculus was removed by manual scraping, and chemotherapeutic agents were used, chlorhexidine 0,12%, chlorhexidine gel 2%, and PVP-I, to control the bacterial flora. The patient is still being monitored after an 8-year follow-up period, the complications associated with periodontal disease decreased, and since the initiation of treatment, the patient has not needed to be hospitalized because of chronic lung disease. This study reports the case of a patient diagnosed with Fraser syndrome and describes the clinical manifestations (general and oral).<\/jats:p>","DOI":"10.1155\/2014\/486108","type":"journal-article","created":{"date-parts":[[2014,12,21]],"date-time":"2014-12-21T21:00:48Z","timestamp":1419195648000},"page":"1-5","source":"Crossref","is-referenced-by-count":3,"title":["Fraser Syndrome-Oral Manifestations and a Dental Care Protocol"],"prefix":"10.1155","volume":"2014","author":[{"given":"Talita Lopes","family":"de Oliveira","sequence":"first","affiliation":[{"name":"Cruzeiro do Sul University (UNICSUL), Rua Jos\u00e9 Garcia de Souza 422, 08673-040 Suzano, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giselle Rodrigues","family":"de Sant\u2019Anna","sequence":"additional","affiliation":[{"name":"Cruzeiro do Sul University, Rua Saturnino dos Santos 106, 04124-150 S\u00e3o Paulo, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"issue":"1","key":"1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1002\/ajmg.1320250111","volume":"25","year":"1986","journal-title":"The American Journal of Medical Genetics"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.39.9.623"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afl109"},{"key":"4","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1111\/j.1469-1809.1962.tb01774.x","volume":"25","year":"1962","journal-title":"Annals of Human Genetics"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1038\/ng1142"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.46.10.629"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1969.00990010640007"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.24.9.549"},{"issue":"1","key":"9","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/ajmg.1320310119","volume":"31","year":"1988","journal-title":"American Journal of Medical Genetics"},{"issue":"3","key":"10","first-page":"231","volume":"74","year":"2007","journal-title":"Journal of Dentistry for Children"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320300317"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1007\/bf01955522"},{"issue":"3","key":"13","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1002\/1096-8628(20010122)98:3<263::AID-AJMG1092>3.0.CO;2-1","volume":"98","year":"2001","journal-title":"American Journal of Medical Genetics"},{"issue":"1","key":"14","first-page":"10","volume":"49","year":"2001","journal-title":"General Dentistry"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1007\/s005400300022"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2004.06.005"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1378\/chest.126.5.1575"},{"key":"18","first-page":"83","volume-title":"Rela\u00e7\u00e3o entre doen\u00e7a periodontal e doen\u00e7as respirat\u00f3rias","year":"2002"},{"key":"19","year":"1995"},{"key":"20","year":"1998"},{"key":"22","first-page":"129","volume-title":"Controle qu\u00edmico da placa dental","year":"1997"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1159\/000246043"},{"key":"24","year":"2005"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1987.58.4.219"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1999.4.1.7"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.2334\/josnusd.47.159"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.2174\/1874210600903010114"},{"issue":"187","key":"29","first-page":"11","year":"2007","journal-title":"Swedish Dental Journal"}],"container-title":["Case Reports in Dentistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crid\/2014\/486108.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crid\/2014\/486108.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crid\/2014\/486108.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,23]],"date-time":"2017-06-23T02:27:39Z","timestamp":1498184859000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crid\/2014\/486108\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":28,"alternative-id":["486108","486108"],"URL":"https:\/\/doi.org\/10.1155\/2014\/486108","relation":{},"ISSN":["2090-6447","2090-6455"],"issn-type":[{"value":"2090-6447","type":"print"},{"value":"2090-6455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}