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Treatment of the different type of vasculitis mainly relies on steroids and immunosuppressive drugs. In case of refractory or relapsing diseases, however, a second line of treatment may be required. Anti-TNF-<jats:italic>\u03b1<\/jats:italic>drugs have been used in this setting during the last 15 years with inconsistent results. We reviewed herein the use of anti-TNF-<jats:italic>\u03b1<\/jats:italic>therapy in different kind of vasculitis and concluded that, except for Behcet\u2019s disease, this therapeutic option has not demonstrated significant improvement in the treatment of vasculitis.<\/jats:p>","DOI":"10.1155\/2014\/493593","type":"journal-article","created":{"date-parts":[[2014,3,3]],"date-time":"2014-03-03T07:58:04Z","timestamp":1393833484000},"page":"1-9","source":"Crossref","is-referenced-by-count":26,"title":["Anti-TNF-Alpha Therapy and Systemic Vasculitis"],"prefix":"10.1155","volume":"2014","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8003-9615","authenticated-orcid":true,"given":"Pierre-Andr\u00e9","family":"Jarrot","sequence":"first","affiliation":[{"name":"Service de M\u00e9decine Interne, H\u00f4pital de la Conception, 147 boulevard Baille, 13005 Marseille, France"},{"name":"INSERM UMR S 1076, UFR Pharmacie, Aix-Marseille-Universit\u00e9, 27 boulevard Jean Moulin, CS 30064, 13385 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