{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:11:17Z","timestamp":1777335077383,"version":"3.51.4"},"reference-count":34,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100001501","name":"University Grants Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001501","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>Present work reports the biological activities of<jats:italic>P. hysterophorus<\/jats:italic>leaf, stem, flower, and root. Dried samples were sequentially extracted with many solvents. Hexane (HX), benzene (BZ), and chloroform (CH) extracts of leaf showed considerable antibacterial activity against<jats:italic>Streptococcus mutans<\/jats:italic>(MTCC 497),<jats:italic>Proteus vulgaris<\/jats:italic>(MTCC 7299), and<jats:italic>Salmonella typhi<\/jats:italic>(MTCC 3917). Flower extracts exhibited presence of higher amount of flavonoids (13.9\u201359.6\u2009<jats:italic>\u03bc<\/jats:italic>gQE\/mg) followed by leaf, stem, and root. Stem (HX, BZ, and CH), leaf ethanol (ET), and root (HX, BZ, and CH) fractions showed noticeable antioxidant capacity in phosphomolybdate assay. Most of the extracts demonstrated beta carotene bleaching inhibition capability. BZ, ethyl acetate (EA), and ET fractions of leaves, stem aqueous (AQ), and flower EA extracts showed membrane protective activities (40\u201355%). Middle fractions of the plant parts displayed moderate antihemolytic potential. Most of the flower extracts exhibited cytotoxic activity (80\u2013100%) against lung and colon cancer cell lines. Root (HX and ET) and leaf ET extracts showed considerable inhibition (90\u201399%) of colon and ovary cancer cell lines. The LC-MS scan demonstrated presence of different compounds showing 3\u201320\u2009min retention time. The study revealed considerable antibacterial, antioxidant, lipo-protective, antihemolytic, and anticancer potential in all parts of<jats:italic>P. hysterophorus<\/jats:italic>.<\/jats:p>","DOI":"10.1155\/2014\/495154","type":"journal-article","created":{"date-parts":[[2014,5,7]],"date-time":"2014-05-07T21:13:23Z","timestamp":1399497203000},"page":"1-10","source":"Crossref","is-referenced-by-count":27,"title":["<i>In Vitro<\/i>Antibacterial, Antioxidant, and Cytotoxic Activities of<i>Parthenium hysterophorus<\/i>and Characterization of Extracts by LC-MS Analysis"],"prefix":"10.1155","volume":"2014","author":[{"given":"Shashank","family":"Kumar","sequence":"first","affiliation":[{"name":"Department of Biochemistry, University of Allahabad, Allahabad 211002, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay","family":"Pandey","sequence":"additional","affiliation":[{"name":"Instrumentation Division, Indian Institute of Integrative Medicine, Jammu 180001, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhay K.","family":"Pandey","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, University of Allahabad, Allahabad 211002, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.5402\/2012\/137289"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/810734"},{"issue":"1","key":"3","first-page":"171","volume":"58","year":"2012","journal-title":"Cellular and Molecular Biology"},{"key":"4","volume":"13, article 120","year":"2013","journal-title":"BMC Complementary and Alternative 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